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Do nerves make bowels irritable?

作者信息

Gulbransen Brian D

机构信息

Neuroscience Program, Department of Physiology, Michigan State University , East Lansing, Michigan.

出版信息

Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G126-G127. doi: 10.1152/ajpgi.00129.2018. Epub 2018 Apr 19.

DOI:10.1152/ajpgi.00129.2018
PMID:29672154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6109704/
Abstract
摘要

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Sigmoid colon mucosal gene expression supports alterations of neuronal signaling in irritable bowel syndrome with constipation.乙状结肠黏膜基因表达支持便秘型肠易激综合征神经元信号改变。
Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G140-G157. doi: 10.1152/ajpgi.00288.2017. Epub 2018 Mar 22.
2
Biomarkers as a diagnostic tool for irritable bowel syndrome: where are we?生物标志物作为肠易激综合征的诊断工具：我们目前的进展如何？
Expert Rev Gastroenterol Hepatol. 2017 Apr;11(4):303-316. doi: 10.1080/17474124.2017.1288096. Epub 2017 Feb 13.
3
The possible role of gastrointestinal endocrine cells in the pathophysiology of irritable bowel syndrome.胃肠内分泌细胞在肠易激综合征病理生理学中的可能作用。
Expert Rev Gastroenterol Hepatol. 2017 Feb;11(2):139-148. doi: 10.1080/17474124.2017.1269601. Epub 2016 Dec 14.
4
Colonic mucosal gene expression and genotype in irritable bowel syndrome patients with normal or elevated fecal bile acid excretion.粪便胆汁酸排泄正常或升高的肠易激综合征患者的结肠黏膜基因表达和基因型
Am J Physiol Gastrointest Liver Physiol. 2015 Jul 1;309(1):G10-20. doi: 10.1152/ajpgi.00080.2015. Epub 2015 Apr 30.
5
Antimicrobial defense of the intestine.肠道的抗菌防御。
Immunity. 2015 Jan 20;42(1):28-39. doi: 10.1016/j.immuni.2014.12.028. Epub 2015 Jan 1.
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A biomarker panel and psychological morbidity differentiates the irritable bowel syndrome from health and provides novel pathophysiological leads.生物标志物谱和心理发病率将肠易激综合征与健康人群区分开来，并提供新的病理生理学线索。
Aliment Pharmacol Ther. 2014 Feb;39(4):426-37. doi: 10.1111/apt.12608. Epub 2014 Jan 6.
7
Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα.鉴定和测试肠易激综合征（IBS）的候选遗传多态性：与 TNFSF15 和 TNFα 的关联。
Gut. 2013 Jul;62(7):985-94. doi: 10.1136/gutjnl-2011-301213. Epub 2012 Jun 8.
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Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis.全球肠易激综合征的患病率和危险因素：一项荟萃分析。
Clin Gastroenterol Hepatol. 2012 Jul;10(7):712-721.e4. doi: 10.1016/j.cgh.2012.02.029. Epub 2012 Mar 15.
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Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome.肠易激综合征患者结肠中发现的黏膜免疫改变。
Clin Gastroenterol Hepatol. 2008 Feb;6(2):194-205. doi: 10.1016/j.cgh.2007.11.012.
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Comprehensive comparison of six microarray technologies.六种微阵列技术的综合比较。
Nucleic Acids Res. 2004 Aug 27;32(15):e124. doi: 10.1093/nar/gnh123.