Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.
Department of Thoracic and Cardiovascular Surgery, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.
PLoS One. 2018 Apr 19;13(4):e0196180. doi: 10.1371/journal.pone.0196180. eCollection 2018.
The precise sizing of the stent graft in thoracic endovascular aortic repair (TEVAR) affects aortic remodeling and hence, further outcome. Covering the proximal entry tear is essential for successful treatment of Type B aortic dissection. Intravascular ultrasound (IVUS) enables real-time aortic diameter assessment, and is especially useful when computed tomography (CT) image quality is poor. IVUS, however, is not routinely utilized due to cost inefficiency. We investigated the impact of IVUS-assisted stent graft sizing on aortic remodeling in TEVAR. In this single-center retrospective study we evaluated patients with Type B aortic dissection undergoing both CT and IVUS before TEVAR. We assessed the aortic diameter at the level of the left subclavian artery via both methods before stent implantation and analyzed due to which method the implanted stent graft was chosen, retrospectively. To determine the degrees of aortic remodeling involved, we evaluated true lumen and false lumen diameters, and total aortic remodeling in CT. We analyzed 45 patients with Type B aortic dissection undergoing TEVAR. The mean ages were 66.9±10.0 years fo0072 IVUS (n = 20) and 62.3±14.2 years for CT-assisted TEVAR (n = 25; p = 0.226). The follow-up time for both groups did not differ between the two groups (IVUS: 22.9±23.1 months, CT: 25.6±23.0 months; p = 0.700). While both methods were associated with advantages regarding aortic remodeling, IVUS-assisted sizing yielded a greater increase in true lumen (30.4±6.2 vs. 25.6±5.3; p = 0.008) and reductions in false lumen (14.4±8.5 vs. 23.9±9.3; p = 0.001) and total aortic diameter (35.5±6.0 vs. 39.9±8.1; p = 0.045). IVUS-guided stent graft sizing in Type B aortic dissection shows beneficial effects on aortic remodeling and might be of additional advantage in aortic diseases, especially when CT image quality is poor.
在胸主动脉腔内修复术(TEVAR)中,支架移植物的精确尺寸会影响主动脉重塑,进而影响进一步的结果。覆盖近端入口撕裂是成功治疗 B 型主动脉夹层的关键。血管内超声(IVUS)可实时评估主动脉直径,在 CT 图像质量较差时尤其有用。然而,由于成本效益不高,IVUS 并未常规使用。我们研究了 IVUS 辅助支架移植物尺寸对 TEVAR 中主动脉重塑的影响。在这项单中心回顾性研究中,我们评估了在 TEVAR 前同时接受 CT 和 IVUS 检查的 B 型主动脉夹层患者。我们在支架植入前通过两种方法评估左锁骨下动脉水平的主动脉直径,并回顾性分析了根据哪种方法选择植入的支架移植物。为了确定涉及的主动脉重塑程度,我们在 CT 上评估了真腔和假腔直径以及总主动脉重塑。我们分析了 45 例接受 TEVAR 的 B 型主动脉夹层患者。IVUS 组(n = 20)的平均年龄为 66.9±10.0 岁,CT 组(n = 25)为 62.3±14.2 岁(p = 0.226)。两组的随访时间无差异(IVUS:22.9±23.1 个月,CT:25.6±23.0 个月;p = 0.700)。虽然两种方法都与主动脉重塑有关,但 IVUS 辅助尺寸测量导致真腔增加更大(30.4±6.2 比 25.6±5.3;p = 0.008),假腔减少(14.4±8.5 比 23.9±9.3;p = 0.001)和总主动脉直径减少(35.5±6.0 比 39.9±8.1;p = 0.045)。B 型主动脉夹层的 IVUS 引导支架移植物尺寸测量对主动脉重塑有有益影响,在主动脉疾病中可能具有额外优势,特别是在 CT 图像质量较差时。