Dobosz Lukasz, Stefaniak Tomasz
Department of General, Endocrine and Transplant Surgery, Gdanski Uniwersytet Medyczny, Gdansk, Poland.
Thorac Cardiovasc Surg. 2019 Aug;67(5):420-424. doi: 10.1055/s-0038-1642029. Epub 2018 Apr 19.
Primary hyperhidrosis is a condition that significantly decreases the quality of life (QOL). Thoracic sympathectomy is safe and efficient method of treatment in palmar hyperhidrosis.
The aim of the study was to evaluate the change in QOL in patients with palmar hyperhidrosis who underwent thoracic sympathectomy.
The study includes 149 patients (37 men and 112 women) who were treated with bilateral thoracoscopic sympathectomy for primary palmar hyperhidrosis. Subjective and objective evaluation of hyperhidrosis were performed prior to the surgery, 3 and 12 months after the treatment. Control group consists of 305 healthy volunteers (118 men and 187 women). The QOL was measured using Functional Assessment of Chronic Illness Therapy (FACIT) scale.
The average level of palmar hyperhidrosis in the study group prior to surgery was 224.69 ± 179.20 mg/min/m. General QOL (FACIT total) before the surgery was significantly lower in the study group when compared with the control group (66.57 ± 16.33 vs. 91.29 ± 11.13; < 0.05). Three months after surgery level of hyperhidrosis decreased significantly and remained at similar level 12 months after the procedure (13.55 ± 15.41 mg/min/m < 0.05 and 14.41 ± 18.19 mg/min/m < 0.05, respectively). After thoracoscopic sympathectomy, the QOL increased and did not differ when compared with the control group 3 and 12 months after the surgery (90.28 ± 11.13 vs. 91.29 ± 11.13; = 0.55 and 89.59 ± 11.34 vs. 91.29 ± 11.13; = 0.84, respectively). The highest increase was observed in functional well-being domain (32.25%); however, it was also noticeable in other domains.
Thoracic sympathectomy is an efficient method of treatment in palmar hyperhidrosis which significantly increases patients' QOL especially in a functional domain.
原发性多汗症是一种显著降低生活质量（QOL）的病症。胸交感神经切除术是治疗掌跖多汗症安全有效的方法。
本研究旨在评估接受胸交感神经切除术的掌跖多汗症患者生活质量的变化。
本研究纳入149例（37例男性和112例女性）因原发性掌跖多汗症接受双侧胸腔镜交感神经切除术的患者。在手术前、治疗后3个月和12个月对多汗症进行主观和客观评估。对照组由305名健康志愿者（118例男性和187例女性）组成。使用慢性病治疗功能评估（FACIT）量表测量生活质量。
研究组术前掌跖多汗症的平均水平为224.69±179.20mg/min/m²。与对照组相比，研究组术前的总体生活质量（FACIT总分）显著较低（66.57±16.33 vs. 91.29±11.13；P<0.05）。术后3个月多汗症水平显著下降，并在术后12个月保持在相似水平（分别为13.55±15.41mg/min/m²，P<0.05和14.41±18.19mg/min/m²，P<0.05）。胸腔镜交感神经切除术后，生活质量提高，术后3个月和12个月与对照组相比无差异（90.28±11.13 vs. 91.29±11.13；P=0.55和89.59±11.34 vs. 91.29±11.13；P=0.84）。在功能幸福感领域观察到最高增幅（32.25%）；然而，在其他领域也很明显。
胸交感神经切除术是治疗掌跖多汗症的有效方法，可显著提高患者的生活质量，尤其是在功能领域。
