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局部进展期横结肠癌局部穿孔并自发性结肠皮肤瘘形成:一项临床挑战。

Localised perforation of locally advanced transverse colon cancer with spontaneous colocutaneous fistula formation: a clinical challenge.

作者信息

Wadhwani Nikita, Diwakar Deepak Kumar

机构信息

Department of General Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

出版信息

BMJ Case Rep. 2018 Apr 19;2018:bcr-2018-224668. doi: 10.1136/bcr-2018-224668.

Abstract

Colon cancer can present with complications such as obstruction, perforation and bleeding. The clinical presentation has been recognised as an independent prognostic factor for morbidity and mortality. We present a rare case of localised perforation of a locally advanced colon cancer arising from mid-transverse colon in an elderly woman in the absence of widely metastatic disease with eventual cutaneous involvement of the overlying skin by direct extension, resulting in formation of colocutaneous fistula. The management of such cases is complex as usually tailored to the situation encountered. This case was a clinical challenge to choose between initial palliative resection and curative R0 resection following neoadjuvant chemotherapy.

摘要

结肠癌可出现肠梗阻、穿孔和出血等并发症。临床表现已被认为是发病率和死亡率的独立预后因素。我们报告了一例罕见病例,一名老年女性发生源于横结肠中部的局部晚期结肠癌局部穿孔,无广泛转移,最终通过直接蔓延导致覆盖皮肤的皮肤受累,形成结肠皮肤瘘。此类病例的处理很复杂,通常需根据具体情况量身定制。该病例在新辅助化疗后是选择初始姑息性切除还是根治性R0切除方面面临临床挑战。

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