Aslan Gonul, Ulger Mahmut, Ulger Seda Tezcan, Durukan Huseyin, Yazici Faik Gurkan, Emekdas Gurol
Department of Medical Microbiology, Faculty of Medicine, Mersin University, Mersin, Turkey.
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Mersin University, Mersin, Turkey.
Int J Reprod Biomed. 2018 Jan;16(1):57-60.
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Genital TB (GTB) is a form of extrapulmonary TB that occurs more frequently in women, in whom it classically presents in association with menstrual irregularity, pregnancy loss and short and long-term sequelae especially infertility in infected women. Patients with GTB are usually young women diagnosed during workup for infertility. GTB is rare in postmenopausal women and responsible for only approximately 1% of postmenopausal bleeding. In this study, we aimed to evaluate the laboratory, clinical and demographic characteristics of female GTB cases.
We presented four female GTB cases with distinct clinical symptoms. All patients have no history of TB, and no acid-fast bacilli were seen in smears prepared from the clinical materials of the patients. Histopathological examinations revealed granulomatous inflammation in all patients.
In the light of the clinical features of these cases we aimed to emphasize that, female GTB must be taken into account in the patients with different clinical symptoms like postmenopausal bleeding, menometrorrhagia, infertility, and menstrual irregularities. We believe that these symptoms will be helpful for the diagnosis and treatment of female GTB.
结核病（TB）是由结核分枝杆菌引起的一种传染病。生殖器结核（GTB）是肺外结核的一种形式，在女性中更为常见，典型表现为月经不规律、流产以及感染女性的短期和长期后遗症，尤其是不孕症。GTB患者通常是在不孕检查过程中被诊断出的年轻女性。GTB在绝经后女性中罕见，仅约占绝经后出血的1%。在本研究中，我们旨在评估女性GTB病例的实验室、临床和人口统计学特征。
我们呈现了4例具有不同临床症状的女性GTB病例。所有患者均无结核病病史，从患者临床材料制备的涂片未发现抗酸杆菌。组织病理学检查显示所有患者均有肉芽肿性炎症。
根据这些病例的临床特征，我们旨在强调，对于出现绝经后出血、月经过多、不孕和月经不规律等不同临床症状的患者，必须考虑女性GTB。我们认为这些症状将有助于女性GTB的诊断和治疗。
