Gittes R F, Foreman R
J. Hartwell Harrison Urology Laboratory, Brigham and Women's Hospital, Boston.
Surg Gynecol Obstet. 1988 Jun;166(6):545-8.
In rats and guinea pigs, transcutaneous through and through mattress sutures of different materials (silk, nylon and Prolene [polypropylene]) were tied under tension to plicate the abdominal wall or the scrotal wall. Knots were either buried subcutaneously or left outside. Monofilament sutures, with buried knots, cut through and became completely incorporated as the plicated normal tissue flattened out to a normal appearance in about three weeks. Silk sutures and bulky outside knots left suppurating sinuses. Histologic examination at seven weeks confirmed the incorporated nylon or Prolene mattress sutures were surrounded by a sheath of clean scar tissue trailing as a curtain back to the cut through skin. It is concluded that sutures of monofilament nylon or Prolene, with buried knots, can be tied under tension to include outside skin and will cut through cleanly to become incorporated without sinus or suppuration. Such incorporated sutures and their trailing curtains of clean scar tissue can provide an internal buttress against soft tissue displacement with potential clinical application.
在大鼠和豚鼠身上，将不同材料（丝线、尼龙线和普理灵[聚丙烯]）的经皮贯穿褥式缝线在张力下打结，以折叠腹壁或阴囊壁。结要么皮下埋置，要么留在外面。带有埋置结的单丝缝线会被切断，并在大约三周内随着折叠的正常组织变平恢复正常外观而完全融入其中。丝线缝线和外面的大结会留下化脓性窦道。七周时的组织学检查证实，融入的尼龙或普理灵褥式缝线被一层干净的瘢痕组织鞘包围，该瘢痕组织鞘像帘子一样向后延伸至皮肤切口处。得出的结论是，带有埋置结的单丝尼龙或普理灵缝线可在张力下打结以包括外部皮肤，并且会干净地切断并融入其中，不会形成窦道或化脓。这种融入的缝线及其干净瘢痕组织的延伸帘子可为软组织移位提供内部支撑，具有潜在的临床应用价值。
