Deakin University, Geelong, Victoria, 3216, Australia.
Epi-Centre for Healthy Ageing, IMPACT SRC, School of Medicine, Deakin University, C/- HERB L3, Barwon Health, PO Box 281, Geelong, Victoria, 3220, Australia.
Arch Osteoporos. 2018 Apr 19;13(1):43. doi: 10.1007/s11657-018-0459-z.
Older men who participated in a sporting activity were less likely to sustain any fracture or major osteoporotic fracture over a 6-year follow-up period.
Regular weight-bearing physical activity can reduce fracture risk through an increase in bone strength, as well as reducing falls risk by improving muscle strength and balance. In this study, we aimed to determine whether a specific type of physical activity, sports participation, reduces fracture risk in older Australian men.
Participation in sporting activities was documented for men aged 60 years and over enrolled in the Geelong Osteoporosis Study situated in south-eastern Australia. Fractures at any skeletal site (excluding skull, face, fingers and toes) and major osteoporotic fracture sites (MOF; wrist, proximal humerus, spine and hip) were ascertained through examination of radiological reports (median follow-up 6.63 years, IQR 5.58-7.29). Multivariable logistic regression was used to investigate the association between sports participation (either binary or continuous) and any fracture or MOF. Other clinical measures and lifestyle variables (such as comorbidity, falls and mobility) were included as potential confounders.
During follow-up, 82 of 656 men (12.5%) sustained at least one fracture at any site and 58 sustained at least one MOF (8.8%). Of those who did and did not fracture (any site), 17 (20.7%) and 204 (35.5%) participated in at least one sporting activity. For MOF, the values were 11 (19.0%) and 210 (35.1%), respectively. Participation in any sporting activity was associated with a reduction in the likelihood of any fracture during follow-up (unadjusted: OR 0.47, 95%CI 0.27-0.83), which persisted after adjusting for other factors (adjusted: OR 0.52, 95%CI 0.29-0.91). The results for MOF were similar (unadjusted: OR 0.43, 0.22-0.85; adjusted 0.48, 0.24-0.95). When considering sports participation as a continuous variable, a trend was observed (adjusted: p = 0.051 and p = 0.059 for any and MOF, respectively). A sensitivity analysis showed similar results when excluding men who reported using a walking aid.
In this group of older men, participation in sporting activity was associated with a reduced risk of fracture during the subsequent follow-up period.
有规律的负重体育活动可以通过增加骨强度来降低骨折风险，还可以通过增强肌肉力量和平衡来降低跌倒风险。在这项研究中，我们旨在确定体育活动这种特定类型的活动是否可以降低澳大利亚老年男性的骨折风险。
对居住在澳大利亚东南部的基隆骨质疏松症研究中年龄在 60 岁及以上的男性进行了体育活动参与情况的记录。通过检查放射学报告确定了任何骨骼部位（不包括颅骨、面部、手指和脚趾）和主要骨质疏松性骨折部位（腕部、肱骨近端、脊柱和髋部）的骨折（中位随访 6.63 年，IQR 5.58-7.29）。多变量逻辑回归用于研究体育活动参与（二进制或连续）与任何骨折或主要骨质疏松性骨折之间的关联。其他临床测量和生活方式变量（如合并症、跌倒和活动能力）被纳入可能的混杂因素。
在随访期间，656 名男性中有 82 名（12.5%）至少发生了一处任何部位的骨折，58 名（8.8%）至少发生了一处主要骨质疏松性骨折。在发生和未发生骨折的患者中，分别有 17 名（20.7%）和 204 名（35.5%）参与了至少一项体育活动。对于主要骨质疏松性骨折，这一数值分别为 11 名（19.0%）和 210 名（35.1%）。在随访期间，参与任何体育活动与降低任何骨折的可能性相关（未调整：OR 0.47，95%CI 0.27-0.83），在调整其他因素后仍然如此（调整后：OR 0.52，95%CI 0.29-0.91）。主要骨质疏松性骨折的结果相似（未调整：OR 0.43，0.22-0.85；调整后：OR 0.48，0.24-0.95）。当考虑体育活动作为一个连续变量时，观察到一种趋势（调整后：任何骨折的 p=0.051，主要骨质疏松性骨折的 p=0.059）。敏感性分析显示，当排除报告使用助行器的男性时，结果相似。
在这组老年男性中，体育活动的参与与随后随访期间骨折风险的降低有关。
