Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743, Jena, Germany.
Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
Macromol Rapid Commun. 2018 Sep;39(17):e1700742. doi: 10.1002/marc.201700742. Epub 2018 Apr 20.
Aspartate incorporated into the protein structure of mussel byssal threads is believed to play an important role, besides the reversible histidine-zinc interactions, in the self-healing behavior of mussel byssal threads. Therefore, copolymers containing both aspartate and histidine moieties are synthesized in order to investigate the influence of aspartate on the complexation of zinc(II) as well as on the self-healing behavior and the mechanical properties of the resulting supramolecular networks. For this purpose, isothermal titration calorimetry measurements of a model aspartate compound as well as of these copolymers are performed and the thermodynamic parameters are utilized for the design of self-healing copolymers. For this purpose, n-lauryl methacrylate-based copolymers containing histidine and aspartate are synthesized and crosslinked with zinc(II) acetate. The self-healing behavior of the supramolecular networks is investigated using scratch healing tests and the mechanical properties by nanoindentation.
天冬氨酸被整合到贻贝足丝蛋白结构中，除了可逆的组氨酸-锌相互作用外，被认为在贻贝足丝的自修复行为中起着重要作用。因此，合成了含有天冬氨酸和组氨酸部分的共聚物，以研究天冬氨酸对锌（II）络合、自修复行为以及所得超分子网络的机械性能的影响。为此，对模型天冬氨酸化合物以及这些共聚物进行了等温滴定 calorimetry 测量，并利用热力学参数来设计自修复共聚物。为此，合成了含组氨酸和天冬氨酸的基于 n-月桂基甲基丙烯酸酯的共聚物，并与乙酸锌交联。通过划痕愈合试验研究超分子网络的自修复行为，通过纳米压痕法研究机械性能。
