Hernández A F, Pla A, Villanueva E
Department of Legal Medicine and Toxicology Service, Faculty of Medicine, University of Granada, Spain.
Arch Toxicol. 1988;61(4):330-1. doi: 10.1007/BF00364859.
Preincubation with Mipafox and Methamidofos as well as Paraoxon (used as control) did not cause inhibition of hexokinase, phosphofructokinase, glyceraldehyde-3-phosphate dehydrogenase and lactate dehydrogenase. This is in contrast with the inhibition of glycolysis by other neurotoxic compounds (hexacarbons, acrylamide, carbon disulfide).
用丙氟磷、甲胺磷以及对氧磷(用作对照)进行预孵育,并未导致己糖激酶、磷酸果糖激酶、甘油醛-3-磷酸脱氢酶和乳酸脱氢酶受到抑制。这与其他神经毒性化合物(六碳化合物、丙烯酰胺、二硫化碳)对糖酵解的抑制形成对比。