Suppr超能文献

神经毒性有机磷化合物丙氟磷和甲胺磷对糖酵解酶缺乏抑制作用。

Lack of inhibition of glycolytic enzymes by the neurotoxic organophosphorus compounds mipafox and methamidofos.

作者信息

Hernández A F, Pla A, Villanueva E

机构信息

Department of Legal Medicine and Toxicology Service, Faculty of Medicine, University of Granada, Spain.

出版信息

Arch Toxicol. 1988;61(4):330-1. doi: 10.1007/BF00364859.

Abstract

Preincubation with Mipafox and Methamidofos as well as Paraoxon (used as control) did not cause inhibition of hexokinase, phosphofructokinase, glyceraldehyde-3-phosphate dehydrogenase and lactate dehydrogenase. This is in contrast with the inhibition of glycolysis by other neurotoxic compounds (hexacarbons, acrylamide, carbon disulfide).

摘要

用丙氟磷、甲胺磷以及对氧磷(用作对照)进行预孵育,并未导致己糖激酶、磷酸果糖激酶、甘油醛-3-磷酸脱氢酶和乳酸脱氢酶受到抑制。这与其他神经毒性化合物(六碳化合物、丙烯酰胺、二硫化碳)对糖酵解的抑制形成对比。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验