Podugol'nikova O A
Genetika. 1988 Mar;24(3):389-95.
The data on nondisjunction of chromosomes in man, and particularly on chromosome 21 in Down syndrome, are presented in this review. New experimental data obtained by the differential staining technique are considered. These data enable us to revise a number of hypotheses on the causes and mechanisms of chromosome nondisjunction.
本综述展示了关于人类染色体不分离的数据,尤其是唐氏综合征中21号染色体的相关数据。文中讨论了通过差异染色技术获得的新实验数据。这些数据使我们能够修正一些关于染色体不分离原因和机制的假说。