Stöhr Mark R, Majeed Raphael W, Günther Andreas
UGMLC, German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.
Stud Health Technol Inform. 2018;247:556-560.
The German Center for Lung Research (DZL) is a research network with the aim of researching respiratory diseases. The participating study sites' register data differs in terms of software and coding system as well as data field coverage. To perform meaningful consortium-wide queries through one single interface, a uniform conceptual structure is required covering the DZL common data elements. No single existing terminology includes all our concepts. Potential candidates such as LOINC and SNOMED only cover specific subject areas or are not granular enough for our needs. To achieve a broadly accepted and complete ontology, we developed a platform for collaborative metadata management. The DZL data management group formulated detailed requirements regarding the metadata repository and the user interfaces for metadata editing. Our solution builds upon existing standard technologies allowing us to meet those requirements. Its key parts are RDF and the distributed version control system Git. We developed a software system to publish updated metadata automatically and immediately after performing validation tests for completeness and consistency.
德国肺部研究中心（DZL）是一个旨在研究呼吸系统疾病的研究网络。参与研究的站点的注册数据在软件、编码系统以及数据字段覆盖范围方面存在差异。为了通过单一接口执行有意义的全联盟范围查询，需要一个涵盖DZL通用数据元素的统一概念结构。现有的术语中没有一个能包含我们所有的概念。诸如LOINC和SNOMED等潜在候选术语仅涵盖特定主题领域，或者粒度不足以满足我们的需求。为了实现一个被广泛接受且完整的本体，我们开发了一个协作式元数据管理平台。DZL数据管理小组针对元数据存储库和元数据编辑的用户界面制定了详细要求。我们的解决方案基于现有的标准技术构建，使我们能够满足这些要求。其关键部分是RDF和分布式版本控制系统Git。我们开发了一个软件系统，在对完整性和一致性进行验证测试后，自动且立即发布更新后的元数据。
