墨西哥城分离出的淋病奈瑟菌的血清群特异性及抗菌药敏性

Serogroup specificity and antimicrobial susceptibilities of Neisseria gonorrhoeae isolated in Mexico City.

作者信息

Conde-Glez C J, Calderón E, Echániz G, Solórzano F, Beltrán M

机构信息

Departamento de Infectología e Immunología Perinatal, Instituto Nacional de Perinatología, Lomas Virreyes, México, D.F.

出版信息

J Antimicrob Chemother. 1988 Apr;21(4):413-6. doi: 10.1093/jac/21.4.413.

DOI:10.1093/jac/21.4.413

PMID:2967809

Abstract

The serogroup pattern of 87 clinical isolates of Neisseria gonorrhoeae was determined by monoclonal coagglutination and the in-vitro activity of seven antimicrobial agents against the same strains was tested by an agar dilution method. The frequency of resistance to spectinomycin, ampicillin, penicillin, erythromycin, chloramphenicol and tetracycline was 14.9%, 33.3%, 34.4%, 30%, 40.2% and 41.3%, respectively. All strains were susceptible to cefotaxime. Out of 87 strains tested, 29.8% produced beta-lactamases and 4.5% were chromosomally resistant to penicillin. In all instances resistance to a drug was associated with serogroup 1-B except for erythromycin. The results presented here correlate with observations made worldwide.

摘要

采用单克隆协同凝集法测定了87株淋病奈瑟菌临床分离株的血清群模式，并通过琼脂稀释法检测了7种抗菌药物对相同菌株的体外活性。对壮观霉素、氨苄西林、青霉素、红霉素、氯霉素和四环素的耐药频率分别为14.9%、33.3%、34.4%、30%、40.2%和41.3%。所有菌株对头孢噻肟敏感。在87株受试菌株中，29.8%产生β-内酰胺酶，4.5%对青霉素具有染色体耐药性。除红霉素外，在所有情况下，对一种药物的耐药性均与1-B血清群有关。此处呈现的结果与全球范围内的观察结果相关。