Gripe Isabella, Danielsson Anna-Karin, Ramstedt Mats
Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden.
The Swedish Council for Information on Alcohol and Other Drugs (CAN), Stockholm, Sweden.
Addiction. 2018 Apr 21. doi: 10.1111/add.14244.
To examine if changes in alcohol consumption are associated with changes in cannabis use among Swedish adolescents in a period of diverging trends, and to investigate if cannabis and alcohol act as complements or substitutes.
DESIGN, SETTING, PARTICIPANTS AND MEASUREMENTS: Data comprise a nationally representative annual school survey of alcohol and drug habits among Swedish 9th-grade students (aged 15-16 years) covering years 1989-2016 (n = 149 603). Alcohol and cannabis use were measured concurrently and alcohol consumption was measured in litres of 100% alcohol per year. Frequency of cannabis use was transformed into a mean using category mid-points. Autoregressive integrated moving average (ARIMA) time-series analysis was used to estimate the association between cannabis and alcohol use. To elucidate changes in the association during the study period, two subperiods (2000-16 and 1989-99) were analysed.
There was a positive and statistically significant association between changes in alcohol consumption and changes in frequency of cannabis use among cannabis users for the period 1989-2016. A 1-litre increase in mean alcohol consumption was associated with a 0.28 increase in frequency of cannabis use (P = 0.010). The corresponding increase for the period 1989-99 was 0.52 (P = 0.003). When restricting the analysis to 2000-16, the association was not statistically significant (P = 0.735). When analysing all adolescents we found no statistically significant association between changes in alcohol consumption and changes in frequency of cannabis use.
From 1989 to 2016 there appears to be a positive association between alcohol and cannabis consumption among Swedish adolescents who use cannabis. This association seems to have become weaker over time, suggesting that alcohol and cannabis are neither substitutes nor complements among Swedish adolescents and that the recent decline in youth drinking is not associated with the increase in frequency of cannabis use.
研究在瑞典青少年中,饮酒量的变化与大麻使用量的变化在趋势不同的时期内是否相关,并调查大麻和酒精是互补品还是替代品。
设计、地点、参与者和测量方法:数据包括对瑞典9年级学生(年龄在15 - 16岁)的酒精和药物使用习惯进行的全国代表性年度学校调查,涵盖1989 - 2016年(n = 149603)。同时测量酒精和大麻的使用情况,酒精消费量以每年纯酒精的升数来衡量。大麻使用频率通过类别中点转化为平均值。采用自回归积分移动平均(ARIMA)时间序列分析来估计大麻和酒精使用之间的关联。为了阐明研究期间关联的变化,分析了两个子时期(2000 - 16年和1989 - 99年)。
在1989 - 2016年期间,大麻使用者中酒精消费量的变化与大麻使用频率的变化之间存在正向且具有统计学意义的关联。平均酒精消费量每增加1升,大麻使用频率增加0.28(P = 0.010)。1989 - 99年期间相应的增加量为0.52(P = 0.003)。当将分析限制在2000 - 16年时,该关联无统计学意义(P = 0.735)。在分析所有青少年时,我们发现酒精消费量的变化与大麻使用频率的变化之间无统计学意义的关联。
从1989年到2016年,在使用大麻的瑞典青少年中,酒精和大麻消费之间似乎存在正向关联。随着时间的推移,这种关联似乎变弱了,这表明在瑞典青少年中,酒精和大麻既不是替代品也不是互补品,并且近期青少年饮酒量的下降与大麻使用频率的增加无关。