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大麻使用障碍与社会经济因素和精神共病的关系:对 1970 年至 2000 年出生的 300 万人的聚类分析。

Cannabis use disorder in relation to socioeconomic factors and psychiatric comorbidity: A cluster analysis of three million individuals born in 1970-2000.

机构信息

Department of Global Public Health, Karolinska Institutet, Sweden.

Centre for Epidemiology and Community Medicine, Sweden.

出版信息

Scand J Public Health. 2023 Feb;51(1):82-89. doi: 10.1177/14034948221122431. Epub 2022 Sep 18.

DOI:10.1177/14034948221122431
PMID:36120841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9903242/
Abstract

BACKGROUND

Cannabis use disorder (CUD) is one of the main reasons for seeking substance use treatment. It is thus important to monitor and increase knowledge of individuals with CUD utilizing healthcare. We aimed to examine the number of CUD diagnoses over time, compare individuals with CUD with those without and identify subgroups based on CUD diagnosis, sex, birth year, socioeconomic factors and psychiatric comorbidity.

METHODS

A Swedish, population-based study with 3,307,759 individuals, born in 1970-2000, with register data extending to 2016. K-mode cluster analysis was used to identify potential subgroups.

RESULTS

The number of individuals with a CUD diagnosis was 14,046 (0.42%). CUD diagnoses increased over time (born 1990-1994: 61 per 100,000, born 1995-2000: 107 per 100,000, by 2016). A majority of those with a CUD had another psychiatric diagnosis (80%, compared with 19% for those without CUD). Four clusters were identified. Cluster 1 comprised mainly men with low income and substance use disorders, clusters 2, 3 and 4 comprised mainly women with higher proportions of mood-related, neurotic and stress-related and behavioural disorders.

CONCLUSIONS

摘要

背景

大麻使用障碍(CUD)是寻求物质使用治疗的主要原因之一。因此,监测和增加对使用医疗保健的 CUD 个体的了解非常重要。我们旨在检查随着时间的推移 CUD 诊断的数量,比较 CUD 患者和无 CUD 患者,并根据 CUD 诊断、性别、出生年份、社会经济因素和精神共病识别亚组。

方法

这是一项基于瑞典人群的研究,共有 3307759 名出生于 1970-2000 年的个体,其登记数据可追溯至 2016 年。采用 K 模式聚类分析来识别潜在的亚组。

结果

CUD 诊断人数为 14046(0.42%)。CUD 诊断数量随着时间的推移而增加(1990-1994 年出生:每 10 万人中有 61 例,1995-2000 年出生:每 10 万人中有 107 例,到 2016 年)。大多数 CUD 患者还有另一种精神诊断(80%,而无 CUD 患者为 19%)。确定了四个聚类。聚类 1 主要包括收入较低且有物质使用障碍的男性,聚类 2、3 和 4 主要包括患有更多情绪相关、神经症和应激相关以及行为障碍的女性。

结论

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da13/9903242/7a167b6fd390/10.1177_14034948221122431-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da13/9903242/7a167b6fd390/10.1177_14034948221122431-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da13/9903242/7a167b6fd390/10.1177_14034948221122431-fig1.jpg

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