Suppr超能文献

一名正在服用贝纳普利治疗类风湿性关节炎的患者发生了肺炎。

pneumonia in a patient taking Benepali for rheumatoid arthritis.

作者信息

Graham Kay Frances, McEntegart Anne

机构信息

Rheumatology, Glasgow Royal Infirmary, Glasgow, UK.

出版信息

BMJ Case Rep. 2018 Apr 21;2018:bcr-2018-224764. doi: 10.1136/bcr-2018-224764.

Abstract

We present a case of a 57-year-old woman who contracted pneumonia while on Benepali, the biosimilar version of etanercept for rheumatoid arthritis. She had seropositive erosive disease. She was admitted to clinic with a 2-week history of dyspnoea, dry cough and fever. Her initial examination showed her to be hypoxic on air with saturations of 77% and left basal crackles. Her admission chest X-ray showed fine reticular shadowing, with an initial suspicion of pulmonary fibrosis. She was empirically treated for community-acquired pneumonia but continued to deteriorate with a worsening type 1 respiratory failure. She was intubated and ventilated on intensive care. The suspicion was raised of pneumonia given her immunosuppression, hypoxic presentation and chest X-ray changes. This was confirmed on sputum PCR. She was treated with a 3-week course of steroids and co-trimoxazole. She was discharged home after a 2-week admission.

摘要

我们报告一例57岁女性病例,该患者在使用类风湿关节炎生物仿制药贝纳利(依那西普的生物仿制药)期间感染了肺炎。她患有血清阳性侵蚀性疾病。她因呼吸困难、干咳和发热2周病史入院。初次检查显示她在空气中缺氧,血氧饱和度为77%,左肺底部有湿啰音。入院时胸部X线显示有细微网状阴影,初步怀疑为肺纤维化。她接受了社区获得性肺炎的经验性治疗,但病情继续恶化,出现了更严重的Ⅰ型呼吸衰竭。她在重症监护室接受了插管和通气治疗。鉴于她的免疫抑制、缺氧表现和胸部X线改变,怀疑是肺炎。痰PCR证实了这一诊断。她接受了为期3周的类固醇和复方新诺明治疗。入院2周后出院回家。

相似文献

本文引用的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验