噻吗洛尔滴眼液对托吡卡胺所致散瞳的作用逆转
Reversal of tropicamide-induced mydriasis by thymoxamine eye drops.
作者信息
McKinna H, Stewart-Jones J H, Edgar D F, Turner P
机构信息
Department of Optometry and Visual Science, City University, London, England.
出版信息
Curr Med Res Opin. 1988;11(1):1-3. doi: 10.1185/03007998809111123.
PMID:2968223
Abstract
In a study in 12 healthy volunteers, local instillation of thymoxamine eye drops (0.5%), completely reversed the mydriasis produced by tropicamide (0.5%), but only incompletely that by tropicamide (1.0%). The difference between these effects was statistically significant (p less than 0.025). The thymoxamine eye drops were well tolerated.
摘要
在一项针对12名健康志愿者的研究中，局部滴入噻吗洛尔滴眼液（0.5%）可完全逆转托吡卡胺（0.5%）引起的散瞳，但对于托吡卡胺（1.0%）引起的散瞳仅能部分逆转。这些效应之间的差异具有统计学意义（p<0.025）。噻吗洛尔滴眼液耐受性良好。
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