从体位性直立性心动过速综合征到影像学孤立综合征。
From Postural Orthostatic Tachycardia Syndrome to Radiologically Isolated Syndrome.
作者信息
Tripathi Richa, Bernitsas Evanthia
机构信息
Emory University School of Medicine, Atlanta, GA, USA.
Wayne State School of Medicine, Detroit, MI, USA.
出版信息
Case Rep Neurol Med. 2018 Feb 25;2018:2956387. doi: 10.1155/2018/2956387. eCollection 2018.
BACKGROUND
Autonomic dysfunction is common in Multiple Sclerosis (MS) patients. Most spinal cord lesions entail some degree of autonomic nervous system dysfunction. MS patients may develop autonomic dysfunction later in their disease course.
METHODS
We report a patient with no prior history of MS presenting with orthostatic symptoms and diagnosed initially with postural orthostatic tachycardia syndrome (POTS). Four months later, she was diagnosed with radiologically isolated syndrome (RIS). The diagnosis was supported by imaging and CSF analysis.
CONCLUSION
Our case sheds light on the need to consider autonomic dysfunction as an initial presentation of demyelinating pathology. Larger trials are needed to outline the possible association between POTS and RIS.
背景
自主神经功能障碍在多发性硬化症（MS）患者中很常见。大多数脊髓病变都伴有一定程度的自主神经系统功能障碍。MS患者可能在疾病后期出现自主神经功能障碍。
方法
我们报告了一名既往无MS病史的患者，该患者出现体位性症状，最初被诊断为体位性直立性心动过速综合征（POTS）。四个月后，她被诊断为影像学孤立综合征（RIS）。影像学和脑脊液分析支持这一诊断。
结论
我们的病例揭示了将自主神经功能障碍视为脱髓鞘病变初始表现的必要性。需要进行更大规模的试验来概述POTS和RIS之间可能的关联。
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