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影响多发性硬化症患者继续间歇性清洁导尿的因素:COSMOS 混合方法研究结果。

Factors affecting continuation of clean intermittent catheterisation in people with multiple sclerosis: Results of the COSMOS mixed-methods study.

机构信息

NMAHP RU, Glasgow Caledonian University, Glasgow, UK.

Faculty of Health Sciences and Sport, University of Stirling, Stirling, UK.

出版信息

Mult Scler. 2019 Apr;25(5):727-739. doi: 10.1177/1352458518768722. Epub 2018 Apr 23.

DOI:10.1177/1352458518768722
PMID:29683042
Abstract

BACKGROUND

Clean intermittent catheterisation (CIC) is often recommended for people with multiple sclerosis (MS).

OBJECTIVE

To determine the variables that affect continuation or discontinuation of the use of CIC.

METHODS

A three-part mixed-method study (prospective longitudinal cohort ( n = 56), longitudinal qualitative interviews ( n = 20) and retrospective survey ( n = 456)) was undertaken, which identified the variables that influenced CIC continuation/discontinuation. The potential explanatory variables investigated in each study were the individual's age, gender, social circumstances, number of urinary tract infections, bladder symptoms, presence of co-morbidity, stage of multiple sclerosis and years since diagnosis, as well as CIC teaching method and intensity.

RESULTS

For some people with MS the prospect of undertaking CIC is difficult and may take a period of time to accept before beginning the process of using CIC. Ongoing support from clinicians, support at home and a perceived improvement in symptoms such as nocturia were positive predictors of continuation. In many cases, the development of a urinary tract infection during the early stages of CIC use had a significant detrimental impact on continuation.

CONCLUSION

Procedures for reducing the incidence of urinary tract infection during the learning period (i.e. when being taught and becoming competent) should be considered, as well as the development of a tool to aid identification of a person's readiness to try CIC.

摘要

背景

清洁间歇性导尿(CIC)常被推荐用于多发性硬化症(MS)患者。

目的

确定影响 CIC 使用持续或停止的变量。

方法

进行了一项三部分混合方法研究(前瞻性纵向队列研究(n=56)、纵向定性访谈研究(n=20)和回顾性调查研究(n=456)),确定了影响 CIC 持续/停止的变量。在每个研究中调查的潜在解释变量包括个体的年龄、性别、社会环境、尿路感染次数、膀胱症状、共存疾病、多发性硬化症阶段和诊断后年限,以及 CIC 教学方法和强度。

结果

对于一些多发性硬化症患者来说,进行 CIC 的前景很困难,在开始使用 CIC 之前可能需要一段时间才能接受。临床医生的持续支持、家庭支持以及夜间尿频等症状的改善被认为是持续使用的积极预测因素。在许多情况下,CIC 使用早期尿路感染的发生对持续使用产生了重大不利影响。

结论

应考虑在学习期间(即接受教学和掌握技能时)减少尿路感染发生率的程序,以及开发一种工具来帮助确定一个人尝试 CIC 的准备情况。

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Mult Scler. 2019 Apr;25(5):727-739. doi: 10.1177/1352458518768722. Epub 2018 Apr 23.
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