三级中心收治的患病新生儿灌注指数与 CRIB 评分的相关性。

Correlation between Perfusion Index and CRIB Score in Sick Neonates Admitted to a Tertiary Center.

机构信息

Department of Neonatology, St. John's Medical College and Hospital, Bangalore, India.

出版信息

J Trop Pediatr. 2019 Feb 1;65(1):84-89. doi: 10.1093/tropej/fmy016.

DOI:10.1093/tropej/fmy016

PMID:29684189

Abstract

OBJECTIVE

The study was to determine the correlation of Perfusion Index (PI) and Clinical Risk Index for Babies (CRIB) score, in assessing the severity of illness in sick neonates.

METHODS

This was a cross-sectional study conducted at a tertiary care Neonatal Intensive Care Unit (NICU). All eligible neonates, both term and preterm, admitted to the high-dependency unit of the NICU were included, after parental consent. Relevant details of history and examination were collected with a structured proforma. Severity of illness was assessed using CRIB score within 12 h of admission. PI was recorded within 24 h of admission, and babies were examined for the presence or absence of shock and their outcome was documented. The correlation coefficient between PI and CRIB score was derived.

RESULTS

A total of 200 eligible newborns were enrolled. The mean gestational age of the neonates was 34 weeks. The median [interquartile range (IQR)] CRIB score was 1.00 (0.00, 3.00), and PI was 1.400 (0.93, 2.30). The Spearman's rank correlation coefficient between PI and CRIB score was -0.41 with p value <0.05. The median PI of neonates with CRIB score ≤5, 6-10 and >10 was 1.50, 0.74, 0.67, respectively (p value <0.0001). The median (IQR) PI of babies with shock and without shock was 0.63 (0.43, 0.84) and 1.58 (1.19, 2.41), respectively, with p value <0.001.

CONCLUSION

PI has a negative correlation with CRIB score and can be used to assess the severity of illness in sick neonates.

摘要

目的

本研究旨在探讨灌注指数（PI）与临床婴儿风险指数（CRIB）评分在评估患病新生儿严重程度方面的相关性。

方法

这是一项在三级保健新生儿重症监护病房（NICU）进行的横断面研究。在获得家长同意后，纳入所有符合条件的入住 NICU 高依赖病房的足月和早产新生儿。使用结构化表格收集病史和检查的相关详细信息。入院 12 小时内采用 CRIB 评分评估疾病严重程度。入院 24 小时内记录 PI，检查婴儿是否存在休克，并记录其结局。得出 PI 与 CRIB 评分之间的相关系数。

结果

共纳入 200 名符合条件的新生儿。新生儿的平均胎龄为 34 周。CRIB 评分中位数（四分位距）为 1.00（0.00，3.00），PI 为 1.400（0.93，2.30）。PI 与 CRIB 评分之间的 Spearman 秩相关系数为-0.41，p 值<0.05。CRIB 评分≤5、6-10 和>10 的新生儿的 PI 中位数（四分位距）分别为 1.50、0.74、0.67（p 值<0.0001）。有休克和无休克的婴儿的 PI 中位数（四分位距）分别为 0.63（0.43，0.84）和 1.58（1.19，2.41），p 值<0.001。