采用超辐射发光二极管（sLED）的光动力疗法治疗光化性角化病。
Photodynamic therapy with the use of superluminescent diodes (sLED) in the treatment of actinic keratosis.
机构信息
Departament of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Poland, Radziwiłłowska 13 St., 20-080 Lublin, Poland.
Departament of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Poland, Radziwiłłowska 13 St., 20-080 Lublin, Poland.
出版信息
Photodiagnosis Photodyn Ther. 2018 Jun;22:187-190. doi: 10.1016/j.pdpdt.2018.04.010. Epub 2018 Apr 22.
BACKGROUND
Superluminescent diodes (sLED) appear to be an innovative and promising light source in photodynamic therapy (PDT), especially in actinic keratosis (AK) lesions treatment.
AIM
Assessment of tolerability and efficacy of sLED in topical 5-aminolevulinic acid (ALA) PDT of AK lesions.
METHODS
27 patients received ALA PDT with the use of sLED with "soft starter".
RESULTS
Tolerability of sLED lamp depended on the treated lesions field (extension) rather than on their thickness. In contrast sLED lamp efficacy depended on AK lesions thickness.
CONCLUSION
sLED PDT is highly effective in the treatment of grade I and II AK lesions. Grade III AK lesions require further treatment.
背景
超辐射发光二极管（sLED）似乎是光动力疗法（PDT）中的一种创新且有前途的光源，特别是在光化性角化病（AK）病变的治疗中。
目的
评估 sLED 在局部 5-氨基酮戊酸（ALA） PDT 治疗 AK 病变中的耐受性和疗效。
方法
27 例患者接受了使用带有“软启动”功能的 sLED 的 ALA-PDT 治疗。
结果
sLED 灯的耐受性取决于治疗的病变区域（范围），而不是病变的厚度。相反，sLED 灯的疗效取决于 AK 病变的厚度。
结论
sLED-PDT 治疗 I 级和 II 级 AK 病变非常有效。III 级 AK 病变需要进一步治疗。
Zotero 插件