在多发性硬化症患者中，阿仑单抗引起的肺炎——一种非传染性呼吸困难的病因。
Pneumonitis secondary to alemtuzumab in a patient with multiple sclerosis - A non-infectious cause of breathlessness.
机构信息
Department of Neurology, Northwick Park Hospital, London, UK.
Department of Respiratory Medicine, Northwick Park Hospital, London, UK.
出版信息
Mult Scler Relat Disord. 2018 May;22:139-140. doi: 10.1016/j.msard.2018.04.002. Epub 2018 Apr 3.
The most common adverse events associated with the monoclonal antibody alemtuzumab are infusion associated reactions and secondary autoimmune disease. Respiratory complications are unusual following treatment with alemtuzumab, but can be precipitated by an infectious cause. We describe a case of a sub-acute steroid responsive non-infectious pneumonitis affecting a 51 year old woman, who presented one month after initiation of therapy for multiple sclerosis with alemtuzumab.
与单克隆抗体阿仑单抗相关的最常见不良反应是输注相关反应和继发性自身免疫性疾病。阿仑单抗治疗后发生呼吸道并发症并不常见，但可由感染引起。我们描述了一例 51 岁女性亚急性类固醇反应性非感染性肺炎，该患者在开始用阿仑单抗治疗多发性硬化症一个月后出现。
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