Noh Soo Min, Shin Ji Hoon, Kim Ha Il, Lee Sun Ho, Chang Kiju, Song Eun Mi, Hwang Sung Wook, Yang Dong Hoon, Ye Byong Duk, Myung Seung Jae, Yang Suk Kyun, Byeon Jeong Sik
Departments of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Departments of Internal Medicine and Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2018 Apr 25;71(4):219-228. doi: 10.4166/kjg.2018.71.4.219.
BACKGROUND/AIMS: The clinical outcomes of angiography and transcatheter arterial embolization (TAE) for acute gastrointestinal bleeding (GIB) have not been completely assessed, especially according to bleeding sites. This study aimed to assess the efficacy of angiography and safety of TAE in acute GIB.
This was a retrospective study evaluating the records of 321 patients with acute GIB who underwent angiography with or without TAE. Targeted TAE was conducted in 134 patients, in whom angiography showed bleeding sources. Prophylactic TAE was performed in 29 patients when the bleeding source was not detected but a specific vessel was strongly suspected by other examinations. The rate of technical success, clinical success, and complications were analyzed.
The detection rate of bleeding source via angiography was 50.8% (163/321), which was not different according to the bleeding sites. The detection rate was higher if the probable bleeding source had already been found by another investigation (59.7% vs. 35.8%, p<0.001). TAE sites were upper GIB in 67, mid GIB in 74, and lower GIB in 22. The technical success rate was 99.3% (133/134), and the clinical success rate was 63.0% (104/163). The prophylactic embolization group showed lower clinical success rate than the targeted embolization group (44.8% vs. 67.9%, p=0.06). The TAE-related complication rate was 12.9% (21/163). Ischemia and/or infarction was more common after TAE for mid and lower GIB than for upper GIB (15.6% vs. 3.0%, p=0.007).
Angiography with or without TAE was an effective method for acute GIB. Targeted embolization should be performed if possible given that it has a higher clinical success rate.
背景/目的:血管造影和经导管动脉栓塞术(TAE)用于急性胃肠道出血(GIB)的临床疗效尚未得到全面评估,尤其是根据出血部位评估。本研究旨在评估血管造影的疗效及TAE治疗急性GIB的安全性。
这是一项回顾性研究,评估了321例接受血管造影(无论是否联合TAE)的急性GIB患者的记录。134例血管造影显示有出血源的患者接受了靶向TAE。29例出血源未被检测到但其他检查强烈怀疑有特定血管出血的患者接受了预防性TAE。分析了技术成功率、临床成功率及并发症情况。
血管造影对出血源的检出率为50.8%(163/321),不同出血部位的检出率无差异。若另一项检查已发现可能的出血源,则血管造影的检出率更高(59.7%对35.8%,p<0.001)。TAE治疗的部位为上消化道出血67例,中消化道出血74例,下消化道出血22例。技术成功率为99.3%(133/134),临床成功率为63.0%(104/163)。预防性栓塞组的临床成功率低于靶向栓塞组(44.8%对67.9%,p=0.06)。TAE相关并发症发生率为12.9%(21/163)。中、下消化道出血TAE术后缺血和/或梗死比上消化道出血更常见(15.6%对3.0%,p=0.007)。
血管造影联合或不联合TAE是治疗急性GIB的有效方法。若可能应进行靶向栓塞,因为其临床成功率更高。