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[射频消融在下肢静脉曲张患者综合外科治疗中的应用]

[Radiofrequency ablation in comprehensive surgical treatment of patients with varicose veins of lower limbs].

作者信息

Dibirov M D, Shimanko A I, Gadzhimuradov R U, Volkov A S, Tiurin D S, Magdiev A Kh

机构信息

Department of Surgical Pathology and Clinical Angiology, Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow, Russia.

Joint Hospital with Polyclinic of the Administration of the RF President's Affairs, Moscow, Russia.

出版信息

Angiol Sosud Khir. 2018;24(1):92-96.

Abstract

Analysed herein are the results of using radiofrequency ablation (RFA) in comprehensive surgical treatment of patients presenting with varicose veins of the lower extremities. The study included a series of ninety-eight 28-to-60-year-old patients (with a total of 105 operations performed) suffering from varicose veins of the lower limbs. Of these, there were 10 men (10.3%) and 88 women (89.7%). Venous disease of clinical class C2 according to the CEAP classification was diagnosed in 80 patients, that of class C3 in 17, and that of class C4a in 1 patient. The procedure of RFA was performed by means of the VNUS device model RF62. The impact was exerted in an automatic mode, maintaining the catheter's temperature at 120° C during a 20-second treatment cycle for each 7 cm of the vein's length. In all cases, each 7-cm-long venous segment to be treated was acted upon 4 times. Forty-five patients after RFA underwent ultrasonographic monitoring performed first on POD 7 and then at 3, 6, 12 and 24 months. Recanalization of the trunk of the great saphenous vein (GSV) was registered in 3 (2.8%) cases at terms up to 3 months after the operation. In 2 cases recanalization turned out to be provoked by an incompetent perforant vein in the lower third of the femur. Seven (6.6%) patients with a large diameter of the great saphenous vein were found to develop post-closure hyperpigmentation which resolved spontaneously 8 months later. The remaining patients, with strict adherence to the indications for RFA, demonstrated complete obliteration of the vessel treated, with no recanalization observed ultrasonographically 10-12 months after the procedure. An additional experimental study with a morphological analysis confirmed appropriateness of carrying out four 20-second treatment cycles of RFA in each segment of the vein. A conclusion was made that RFA used in comprehensive surgical treatment for varicose veins of the lower limbs makes it possible to attain good therapeutic and cosmetic results that persist over time, if conducted in compliance with the mentioned fundamentally essential peculiarities of performing the procedure.

摘要

本文分析了在下肢静脉曲张患者综合手术治疗中使用射频消融(RFA)的结果。该研究纳入了98例28至60岁的下肢静脉曲张患者(共进行了105次手术)。其中,男性10例(10.3%),女性88例(89.7%)。根据CEAP分类,80例患者被诊断为临床C2级静脉疾病,17例为C3级,1例为C4a级。RFA手术采用RF62型VNUS设备进行。以自动模式施加作用,在每个7厘米长的静脉段20秒的治疗周期内将导管温度维持在120°C。在所有情况下,每个7厘米长的待治疗静脉段作用4次。45例接受RFA治疗的患者在术后第7天以及3、6、12和24个月接受了超声监测。在术后3个月内,大隐静脉主干再通3例(2.8%)。其中2例再通是由股骨下三分之一处功能不全的穿通静脉引起的。7例(6.6%)大隐静脉直径较大的患者出现了闭合后色素沉着,8个月后自行消退。其余严格遵循RFA适应证的患者,治疗的血管完全闭塞,术后10至12个月超声检查未观察到再通。一项额外的形态学分析实验研究证实了在静脉的每个节段进行4个20秒RFA治疗周期的合理性。得出的结论是,如果按照上述执行该手术的基本关键特性进行操作,RFA用于下肢静脉曲张的综合手术治疗能够获得良好的治疗和美容效果,且效果持久。

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