Gomółka Ewa, Radomska Monika, Bielska Dorota Emilia
Przegl Lek. 2016;73(10):795-7.
Spreading e-cigarettes popularity comes from relief, the products are safe. They don’t contain carcinogenic substances, that are present in tobacco smoke. But nicotine present in e-liquid is a very toxic alkaloid, highly addictive. A case of acute, oral intoxication with e-liquid was described. A patient, 42-years old woman, e-cigarettes addicted, health thus far, by accident drunk a swig of e-liquid containing nicotine at concentration 6 mg/ml. At admission to Toxicology Department she was conscious, with symptoms: dizziness, flushed cheeks, dry skin, dry conjunctivas, medium-wide pupils, nervous twitch, tachycardia, elevated blood pressure. Concentration of cotinine – nicotine metabolite, in serum and urine were respectively 2077 and 10236 ng/ml. Applied treatment was: infusive liquids, intravenous alkalization, administration of electrolytes and propranolol. Gradually improvement was reached and on the third day of hospitalization, after psychiatric consultation she was deinstitutionalized in good medical condition to continue treatment in Neurology Clinic. E-fluid intoxications are rare, poisoning course depends on nicotine dose, way of absorption, patient’s health state and age.
电子烟的流行源于人们认为其产品安全。它们不含有烟草烟雾中存在的致癌物质。但是电子烟液中含有的尼古丁是一种剧毒生物碱，极易上瘾。本文描述了一例电子烟液急性口服中毒的病例。一名42岁的女性患者，有电子烟成瘾史，偶然间误饮了一口浓度为6毫克/毫升的含尼古丁电子烟液。入住毒理学科室时，她意识清醒，症状包括：头晕、脸颊潮红、皮肤干燥、结膜干燥、瞳孔中度散大、神经抽搐、心动过速、血压升高。血清和尿液中可替宁（尼古丁代谢物）的浓度分别为2077纳克/毫升和10236纳克/毫升。采取的治疗措施包括：输液、静脉碱化、补充电解质和使用普萘洛尔。病情逐渐好转，住院第三天，经精神科会诊后，她在医疗状况良好的情况下出院，转至神经科诊所继续治疗。电子烟液中毒较为罕见，中毒过程取决于尼古丁剂量、吸收方式、患者的健康状况和年龄。
