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氟尿嘧啶区域灌注治疗结直肠癌肝转移

Regional infusion of fluoropyrimidines for hepatic metastases of colorectal cancer.

作者信息

Koks C H, Brouwers J R, Sleijfer D T

机构信息

Department of Clinical Pharmacy, General Hospital De Tjongerschans, Heerenveen, The Netherlands.

出版信息

Pharm Weekbl Sci. 1988 Apr 22;10(2):69-75. doi: 10.1007/BF01962681.

Abstract

Recent reports on regional chemotherapy for hepatic metastases of colorectal origin are reviewed. Because of reported side effects and lack of evidence for its superiority over conventional intravenous administration, intra-arterial administration of fluoropyrimidines cannot be advised for routine use, but should be restricted to centres participating in clinical trials on this subject.

摘要

本文综述了近期关于结直肠癌肝转移区域化疗的报道。鉴于有报道称其存在副作用且缺乏优于传统静脉给药的证据,氟嘧啶动脉内给药不建议常规使用,而应仅限于参与该主题临床试验的中心。

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