Nelson David V, Esty Mary Lee
1 Sam Houston State University, Huntsville, TX, USA.
2 Brain Wellness and Biofeedback Center of Washington, Bethesda, MD, USA.
J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18770136. doi: 10.1177/2515690X18770136.
Research regarding noninvasive brain stimulation technologies for the treatment of mild traumatic brain injury (mTBI), posttraumatic stress disorder (PTSD), and mixed (mTBI/PTSD) trauma syndromes has been increasing exponentially. Technologies with the greatest potential thus far include repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), and cranial electrotherapy stimulation (CES). The nature and some of the controversies distinguishing mTBI, PTSD, and mTBI/PTSD are reviewed along with evidence for shared underlying mechanisms. An overview of treatment applications for rTMS, tDCS, and CES are also reviewed. A novel variant of a minute pulsed electromagnetic stimulation technology linked to ongoing electroencephalograph monitoring known as the Flexyx Neurotherapy System is introduced with an overview of the technology and technique, as well as a summary of supportive data to date that explores potential applications for amelioration of these syndromes.
关于用于治疗轻度创伤性脑损伤(mTBI)、创伤后应激障碍(PTSD)以及混合性(mTBI/PTSD)创伤综合征的非侵入性脑刺激技术的研究呈指数级增长。迄今为止,最具潜力的技术包括重复经颅磁刺激(rTMS)、经颅直流电刺激(tDCS)和颅电刺激疗法(CES)。本文回顾了区分mTBI、PTSD和mTBI/PTSD的本质及一些争议点,并阐述了其潜在共同机制的相关证据。同时,还综述了rTMS、tDCS和CES的治疗应用概况。此外,还介绍了一种与正在进行的脑电图监测相关的微小脉冲电磁刺激技术的新型变体——Flexyx神经治疗系统,概述了该技术和操作方法,以及迄今为止支持性数据的总结,探讨了其改善这些综合征的潜在应用。