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经阴道超声引导精准转移方法的建立。

Establishment of a trans-vaginal ultrasound-guided pinpoint transfer method.

作者信息

Okamoto Sumihide

机构信息

ART Okamoto Women's Clinic Nagasaki City Japan.

出版信息

Reprod Med Biol. 2018 Mar 8;17(2):182-187. doi: 10.1002/rmb2.12091. eCollection 2018 Apr.

DOI:10.1002/rmb2.12091
PMID:29692676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5902464/
Abstract

PURPOSE

Through the use of the trans-vaginal ultrasound-guided pinpoint transfer method, the aim was to ensure the safety of the embryo being transferred in cases of difficult cervixes. It also was aimed to be able to stop embryo transfers in difficult cases and to be able to restart the process under anesthesia or cryopreservation.

METHODS

A new type of transfer catheter was developed. With this method, after reaching the internal os, the embryologist begins the loading of the embryo into the inner catheter. Then, the embryo transfer begins. Under the guidance of the trans-vaginal ultrasonography, the optimal position for implantation is selected.

RESULTS

Out of 666 cases, 14 were difficult cervixes. This transfer method enabled 221 of the 666 patients to become pregnant successfully, which was a success rate of 33.2%.

CONCLUSION

From start to finish, this method takes only 2 min. It is simple, fast, and reliable, with a high satisfaction rate amongst patients.

摘要

目的

通过经阴道超声引导下的精准移植方法，旨在确保在宫颈情况复杂的病例中胚胎移植的安全性。同时，目标是能够在困难病例中停止胚胎移植，并能够在麻醉或冷冻保存的情况下重新开始该过程。

方法

研发了一种新型移植导管。采用这种方法，到达宫颈内口后，胚胎学家开始将胚胎装入内导管。然后开始胚胎移植。在经阴道超声检查的引导下，选择最佳着床位置。

结果

在666例病例中，有14例宫颈情况复杂。这种移植方法使666例患者中的221例成功怀孕，成功率为33.2%。

结论

该方法从开始到结束仅需2分钟。它简单、快速且可靠，患者满意度高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/48f5ab67c716/RMB2-17-182-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/6e41bdf7e73b/RMB2-17-182-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/eb80576a14b4/RMB2-17-182-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/5fb82ca5b01b/RMB2-17-182-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/48f5ab67c716/RMB2-17-182-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/6e41bdf7e73b/RMB2-17-182-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/eb80576a14b4/RMB2-17-182-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/5fb82ca5b01b/RMB2-17-182-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be5/5902464/48f5ab67c716/RMB2-17-182-g004.jpg

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本文引用的文献

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Transvaginal versus transabdominal ultrasound guidance for embryo transfer in donor oocyte recipients: a randomized clinical trial.经阴道与经腹超声引导在供卵受者胚胎移植中的应用：一项随机临床试验。
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Fertil Steril. 2008 Oct;90(4):1187-90. doi: 10.1016/j.fertnstert.2007.07.1344. Epub 2008 Apr 25.
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A randomized controlled clinical trial of 2295 ultrasound-guided embryo transfers.
一项针对2295例超声引导下胚胎移植的随机对照临床试验。
Hum Reprod. 2008 May;23(5):1101-6. doi: 10.1093/humrep/den064. Epub 2008 Mar 5.
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Among women undergoing embryo transfer, is the probability of pregnancy and live birth improved with ultrasound guidance over clinical touch alone? A systemic review and meta-analysis of prospective randomized trials.在接受胚胎移植的女性中，与单纯临床触诊相比，超声引导是否能提高妊娠和活产的概率？一项对前瞻性随机试验的系统评价和荟萃分析。
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Optimizing the embryo transfer technique.优化胚胎移植技术。
Hum Reprod. 2002 May;17(5):1149-53. doi: 10.1093/humrep/17.5.1149.
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Transvaginal ultrasound-guided embryo transfer improves outcome in patients with previous failed in vitro fertilization cycles.经阴道超声引导下胚胎移植可改善既往体外受精周期失败患者的结局。
Fertil Steril. 2002 Apr;77(4):769-75. doi: 10.1016/s0015-0282(01)03279-4.
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Transvaginal ultrasound-guided embryo transfer improves pregnancy and implantation rates after IVF.
Hum Reprod. 2001 Dec;16(12):2578-82. doi: 10.1093/humrep/16.12.2578.
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What factors are important for successful embryo transfer after in-vitro fertilization?
Hum Reprod. 1999 Mar;14(3):590-2. doi: 10.1093/humrep/14.3.590.
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Ultrasound tracking of the movement of embryo-associated air bubbles on standing after transfer.胚胎移植后静置时与胚胎相关的气泡运动的超声追踪。
Hum Reprod. 1998 Aug;13(8):2107-9. doi: 10.1093/humrep/13.8.2107.
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Potentially important variables identified by transvaginal ultrasound-guided embryo transfer.经阴道超声引导下胚胎移植所识别的潜在重要变量。
Hum Reprod. 1997 May;12(5):963-6. doi: 10.1093/humrep/12.5.963.