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在阿尔及利亚布利达的弗朗茨·法农医院对患者入院时耐甲氧西林情况进行鼻腔携带筛查。

Screening of nasal carriage of methicillin-resistant during admission of patients to Frantz Fanon Hospital, Blida, Algeria.

作者信息

Ouidri Mohamed Amine

机构信息

University of Blida, Blida, Algeria.

出版信息

New Microbes New Infect. 2018 Feb 22;23:52-60. doi: 10.1016/j.nmni.2018.02.006. eCollection 2018 May.

Abstract

A study was performed of and methicillin-resistant (MRSA) strains isolated from nasal preoperative samples. Of 663 samples assessed, staphylococcus was detected in 143 (21.57%). The disc diffusion method (cefoxitin 30 μg), a screening test (oxacillin 6 μg/mL) and a search for Protein Binding Additional Penicillin 2 (PLP2a) allowed the detection and confirmation of resistance to methicillin for 36 strains, a rate of 5.43% of the total population studied. Eight MRSA carriers received care in the trauma service, 14 in cardiology, five in ear, nose and throat, four in neurosurgery and paediatrics, and one in SCI. Thirty-six methicillin-resistant of the nasal portage strains are in their great majority, 27 of 36, rather limited multi-R character (two to three families namely resistance: tetracyclines, fluoroquinolones, aminoglycosides, macrolides). One of the MRSA strains was found to have intermediate sensitivity to vancomycin.

摘要

对从术前鼻腔样本中分离出的金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌(MRSA)菌株进行了一项研究。在评估的663个样本中,有143个(21.57%)检测到葡萄球菌。采用纸片扩散法(头孢西丁30μg)、筛选试验(苯唑西林6μg/mL)以及对蛋白结合附加青霉素2(PLP2a)的检测,对36株菌株检测并确认了对甲氧西林的耐药性,占所研究总人口的5.43%。8名MRSA携带者在创伤科接受治疗,14名在心脏病科,5名在耳鼻喉科,4名在神经外科和儿科,1名在脊髓损伤科。36株鼻腔携带的耐甲氧西林菌株绝大多数具有相当有限的多重耐药特性(两到三类耐药:四环素类、氟喹诺酮类、氨基糖苷类、大环内酯类),36株中有27株。发现其中一株MRSA菌株对万古霉素具有中度敏感性。

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