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[植入式心脏复律除颤器患者的室性心律失常及设备干预分析:在扩张型心肌病心脏性猝死一级预防的遥测随访中,有/无再同步治疗]

[Ventricular arrhythmia and device intervention analysis in patients with implanted cardioverter-defibrillator with/without resynchronisation therapy in dilative cardiomyopathy in primary prevention of sudden cardiac death in telemetric follow-up].

作者信息

Lelakowski Jacek, Rydlewska Anna, Lelakowska Maria, Pudło Joanna, Piekarz Justyna

出版信息

Przegl Lek. 2016;73(11):830-6.

PMID:29693364
Abstract

INTRODUCTION

Remote monitoring of ICD/CRTD is safe, during which evaluates the type of arrhythmia, intervention.

AIM

The aim of the study was the assessment of ventricular arrhythmia and ICD/CRTD intervention.

MATERIAL AND METHODS

The study included 177 patients (mean age 61,1±13; 23-88 y; Men 141) with an ICD/CRTD implanted. Patients were controlled telemonitoring system, Medtronic Carelink. The following variables were analyzed: age, gender, comorbidities, LVEF value, NYHA class, type of ventricular arrhythmias, device interventions, reprogramming and pharmacotherapy changes.

RESULTS

In multivariate analysis, it was found that, diabetes mellitus (HR 3,49), a low ejection fraction <25% (HR 2,51) predispose to ventricular arrhythmias; and a low ejection fraction <25% (HR 1,88), ischemic DCM (HR 1,92), II NYHA class, the lack of Amiodarone (HR 5,01) predispose to device intervention.

CONCLUSIONS

  1. A low ejection fraction, ischemic dilative cardiomyopathy, II NYHA class, the lack treatment of Amiodarone predispose to ventricular arrhythmias. 2. A low ejection fraction, diabetes mellitus predispose to device intervention. 3. A significant correlation between interventions and ventricular arrhythmias, renal failure, diabetes mellitus, abnormal lipidogram were observed. 4. Telemetric follow-up of cardiac implantable devices is a safe and enables quick information transmission in cases of clinical complications (arrhythmias, interventions).
摘要

引言

植入式心律转复除颤器(ICD)/心脏再同步治疗除颤器(CRTD)的远程监测是安全的,在此期间可评估心律失常的类型及干预措施。

目的

本研究旨在评估室性心律失常及ICD/CRTD干预情况。

材料与方法

该研究纳入了177例植入ICD/CRTD的患者(平均年龄61.1±13岁;23 - 88岁;男性141例)。患者通过美敦力Carelink远程监测系统进行管理。分析了以下变量:年龄、性别、合并症、左心室射血分数(LVEF)值、纽约心脏协会(NYHA)心功能分级、室性心律失常类型、设备干预、重新编程及药物治疗变化。

结果

多因素分析发现,糖尿病(风险比[HR] 3.49)、低射血分数<25%(HR 2.51)易引发室性心律失常;低射血分数<25%(HR 1.88)、缺血性扩张型心肌病(HR 1.92)、NYHA II级、未使用胺碘酮(HR 5.01)易导致设备干预。

结论

  1. 低射血分数、缺血性扩张型心肌病、NYHA II级、未使用胺碘酮治疗易引发室性心律失常。2. 低射血分数、糖尿病易导致设备干预。3. 观察到干预与室性心律失常、肾衰竭、糖尿病、血脂异常之间存在显著相关性。4. 心脏植入式设备的远程随访是安全的,且在临床并发症(心律失常、干预)发生时能够快速传输信息。

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