Tamano K, Shimizu T, Hamazaki N, Yamamoto H, Yagi S
Department of Medicine, Dokkyo University School of Medicine, Tochigi.
J Cardiol. 1987 Sep;17(3):597-605.
We investigated the relationship between parameters of left ventricular diastolic filling using pulsed Doppler echocardiography and the A wave ratio of apexcardiography (ACG), and then evaluate the characteristic features of diastolic behavior in hypertrophic hearts and in various cardiac diseases. The study population consisted of 68 patients and 25 normal subjects, and included 19 cases of chronic renal failure (CRF), 17 cases of ischemic heart disease (IHD), 16 cases of hypertension (HT), six cases of hypertrophic cardiomyopathy, two cases of aortic stenosis, two cases of arrhythmias, and six of other cardiac diseases. The A wave ratio of ACG was calculated as the ratio of A wave amplitude and total excursion [(A/E-O) x 100]. At the same time, the peak early filling velocity (R), the peak late filling velocity (A), the ratio of R to A (A/R), acceleration time (AT), and deceleration time (DT) were measured from the left ventricular inflow velocity pattern using pulsed Doppler echocardiography. The results were as follows: 1. There was a close positive correlation between the A wave ratio of ACG and the A/R of pulsed Doppler echocardiography. 2. In patients with left ventricular hypertrophy (LVH), both the A wave ratio and the A/R were significantly higher than those in normal subjects. And in LVH with asynergy, both the A wave ratio and the A/R were significantly higher than those in LVH without asynergy. 3. In CRF, IHD, and HT, both the A wave ration and the A/R were significantly higher than those in normal subjects, but there were no significant differences among these three disease entities.(ABSTRACT TRUNCATED AT 250 WORDS)
我们使用脉冲多普勒超声心动图研究了左心室舒张期充盈参数与心尖心动图(ACG)A波比值之间的关系,进而评估肥厚型心脏及各种心脏疾病中舒张功能的特征。研究对象包括68例患者和25名正常受试者,其中有19例慢性肾衰竭(CRF)、17例缺血性心脏病(IHD)、16例高血压(HT)、6例肥厚型心肌病、2例主动脉瓣狭窄、2例心律失常以及6例其他心脏疾病。ACG的A波比值计算为A波振幅与总偏移的比值[(A/E - O)×100]。同时,使用脉冲多普勒超声心动图从左心室流入速度模式测量早期充盈峰值速度(R)、晚期充盈峰值速度(A)、R与A的比值(A/R)、加速时间(AT)和减速时间(DT)。结果如下:1. ACG的A波比值与脉冲多普勒超声心动图的A/R之间存在密切正相关。2. 在左心室肥厚(LVH)患者中,A波比值和A/R均显著高于正常受试者。并且在伴有运动失调的LVH中,A波比值和A/R均显著高于无运动失调的LVH。3. 在CRF、IHD和HT中,A波比值和A/R均显著高于正常受试者,但这三种疾病之间无显著差异。(摘要截断于250字)