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Propafenone Overdose: From Cardiogenic Shock to Brugada Pattern.

作者信息

Gil Julio, Marmelo Bruno, Abreu Luís, Antunes Hugo, Santos Luís Ferreira Dos, Cabral José Costa

机构信息

Serviço de Cardiologia, Centro Hospitalar Tondela, Viseu, Portugal.

出版信息

Arq Bras Cardiol. 2018 Mar;110(3):292-294. doi: 10.5935/abc.20180033.

DOI:10.5935/abc.20180033
PMID:29694554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5898781/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcd/5898781/7190e99e96a7/abc-110-03-0292-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcd/5898781/986778202eee/abc-110-03-0292-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcd/5898781/7190e99e96a7/abc-110-03-0292-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcd/5898781/986778202eee/abc-110-03-0292-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fcd/5898781/7190e99e96a7/abc-110-03-0292-g02.jpg

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1
Propafenone Overdose: From Cardiogenic Shock to Brugada Pattern.普罗帕酮过量：从心源性休克到 Brugada 综合征心电图表现
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Pediatric extracorporeal cardiopulmonary resuscitation settled in an emergency department for a propafenone intentional intoxication.儿科体外心肺复苏术在急诊科治疗普罗帕酮药物中毒。
Am J Emerg Med. 2018 Nov;36(11):2132.e1-2132.e3. doi: 10.1016/j.ajem.2018.08.001. Epub 2018 Aug 3.
3
Brugada syndrome, Brugada phenocopy or none?Brugada综合征、Brugada综合征拟表型还是两者皆无？
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Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report.
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Propafenone poisoning--a case report with plasma propafenone concentrations.普罗帕酮中毒——附一例血浆普罗帕酮浓度检测报告。
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Flecainide overdose causing a Brugada-type pattern on electrocardiogram in a previously well patient.氟卡尼过量在一名既往健康的患者心电图上导致 Brugada 型图形。
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Unintentional pediatric overdose of propafenone.儿童意外过量服用普罗帕酮。
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Propafenone-induced cardiac arrest: full recovery with insulin, is it possible?普罗帕酮诱发的心脏骤停：使用胰岛素后完全恢复，这有可能吗？
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[Ventricular fibrillation and Brugada-like ECG pattern during propafenone treatment].
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Can QRS Widening be a result of propafenone overdose?
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引用本文的文献

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A Tissue Distribution Study of Propafenone in an Intentional Fatal Poisoning Case.在一个故意中毒致死案例中普罗帕酮的组织分布研究。
Int J Mol Sci. 2024 May 10;25(10):5202. doi: 10.3390/ijms25105202.
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Novel Arylpiperazine Derivatives of Salicylamide with α-Adrenolytic Properties Showed Antiarrhythmic and Hypotensive Properties in Rats.新型芳基哌嗪水杨酰胺衍生物具有α-肾上腺素能阻滞特性，在大鼠中表现出抗心律失常和降压作用。
Int J Mol Sci. 2022 Dec 24;24(1):293. doi: 10.3390/ijms24010293.
3
Propafenone and propranolol dual toxicity.普罗帕酮与普萘洛尔双重毒性

本文引用的文献

1
[Concealed Brugada syndrome that became apparent incidentally during atrial fibrillation therapy].[隐匿性 Brugada 综合征在房颤治疗期间偶然显现]
Turk Kardiyol Dern Ars. 2011 Mar;39(2):159-62. doi: 10.5543/tkda.2011.01131.
2
Propafenone overdose: cardiac arrest and full recovery.普罗帕酮过量：心脏骤停与完全恢复。
Cardiol J. 2010;17(6):619-22.
3
Successful treatment of suicidal mega dose of propafenone intoxication - a case report.成功救治超大剂量普罗帕酮自杀中毒——1例病例报告
J Am Coll Emerg Physicians Open. 2020 Jun 11;1(5):1104-1107. doi: 10.1002/emp2.12126. eCollection 2020 Oct.
Kardiol Pol. 2010 Nov;68(11):1284-5.
4
Acute intoxication with propafenone and trimethoprim-sulfamethoxazole in a case of suicide attempt.一例自杀未遂患者中普罗帕酮与甲氧苄啶-磺胺甲恶唑急性中毒情况
Turk Kardiyol Dern Ars. 2009 Sep;37(6):410-3.
5
Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.布加综合征：第二届共识会议报告：得到心律学会和欧洲心律协会认可。
Circulation. 2005 Feb 8;111(5):659-70. doi: 10.1161/01.CIR.0000152479.54298.51. Epub 2005 Jan 17.
6
Flecainide and propafenone induced ST-segment elevation in patients with atrial fibrillation: clue to specificity of Brugada-type electrocardiographic changes.氟卡尼和普罗帕酮可导致心房颤动患者ST段抬高：Brugada型心电图改变特异性的线索
Am J Cardiol. 2004 Nov 1;94(9):1184-5. doi: 10.1016/j.amjcard.2004.07.091.
7
Acute toxicity of propafenone in a case of suicidal attempt.
Bratisl Lek Listy. 2004;105(1):14-7.
8
Fatal propafenone overdoses: case reports and a review of the literature.普罗帕酮致死性过量：病例报告及文献综述
J Anal Toxicol. 2003 Nov-Dec;27(8):595-9. doi: 10.1093/jat/27.8.595.
9
Unmasking effect of propafenone on the concealed form of the Brugada phenomenon.
Pacing Clin Electrophysiol. 2000 Mar;23(3):416-8. doi: 10.1111/j.1540-8159.2000.tb06774.x.
10
Clinical pharmacology of propafenone.普罗帕酮的临床药理学。
Circulation. 1983 Sep;68(3):589-96. doi: 10.1161/01.cir.68.3.589.