Ker Wilter Dos Santos, Nunes Thais Helena Peixoto, Nacif Marcelo Souto, Mesquita Claudio Tinoco
Setor de Medicina Nuclear, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Serviço de Radiologia, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Arq Bras Cardiol. 2018 Mar;110(3):278-288. doi: 10.5935/abc.20180051.
Many non-invasive methods, such as imaging tests, have been developed aiming to add a contribution to existing studies in estimating patients' prognosis after myocardial injury. This prognosis is proportional to myocardial viability, which is evaluated in coronary artery disease and left ventricular dysfunction patients only. While myocardial viability represents the likelihood of a dysfunctional muscle (resulting from decreased oxygen supply for coronary artery obstruction), hibernation represents post-interventional functional recovery itself. This article proposes a review of pathophysiological basis of viability, diagnostic methods, prognosis and future perspectives of myocardial viability. An electronic bibliographic search for articles was performed in PubMed, Lilacs, Cochrane and Scielo databases, according to pre-established criteria. The studies showed the ability of many imaging techniques in detecting viable tissues in dysfunctional areas of left ventricle resulting from coronary artery injuries. These techniques can identify patients who may benefit from myocardial revascularization and indicate the most appropriate treatment.
许多非侵入性方法,如成像测试,已被开发出来,旨在为现有的关于估计心肌损伤后患者预后的研究做出贡献。这种预后与心肌活力成正比,而心肌活力仅在冠状动脉疾病和左心室功能障碍患者中进行评估。虽然心肌活力代表了功能失调的心肌(由于冠状动脉阻塞导致氧气供应减少)的可能性,但心肌冬眠本身代表了介入后的功能恢复。本文对心肌活力的病理生理基础、诊断方法、预后及未来展望进行综述。根据预先设定的标准,在PubMed、Lilacs、Cochrane和Scielo数据库中对文章进行了电子文献检索。研究表明,许多成像技术能够检测出由冠状动脉损伤导致的左心室功能障碍区域的存活组织。这些技术可以识别可能从心肌血运重建中获益的患者,并指明最合适的治疗方法。