Donofrio Mary T
Division of Cardiology, Fetal Heart Program, Children's National Health System, Washington, District of Columbia.
Am J Perinatol. 2018 May;35(6):549-552. doi: 10.1055/s-0038-1637764. Epub 2018 Apr 25.
Advances in prenatal imaging have improved the examination of the fetal cardiovascular system. Fetal echocardiography facilitates the prenatal diagnosis of congenital heart disease (CHD) and through sequential examination, allows assessment of fetal cardiac hemodynamics, predicting the evolution of anatomical and functional cardiovascular abnormalities in utero and during the transition to a postnatal circulation at delivery. This approach allows detailed diagnosis with prenatal counseling and enables planning to define perinatal management, selecting the fetuses at a risk of postnatal hemodynamic instability who are likely to require a specialized delivery plan. The prenatal diagnosis and management of critical neonatal CHD has been shown to play an important role in improving the outcome of newborns with these conditions, allowing timely stabilization of the circulation prior to cardiac intervention or surgery, thus reducing the risk of perioperative morbidity and mortality. Diagnostic protocols aimed at risk-stratifying severity and potential postnatal compromise in fetuses with CHD have been developed to identify those who may require special intervention at birth or within the first days of life. In addition, new methodologies are being studied to improve the accuracy of prediction of disease severity. Perinatal management of neonates with a prenatal diagnosis of CHD requires a close collaboration between obstetric, neonatal, and cardiology services. In this article, the management of fetuses with CHD will be discussed, along with summarizing the in utero and fetal echocardiographic findings used for risk stratification of newborns with CHD and reviewing the basic principles used for planning for neonatal resuscitation and initial transitional care of these complex newborns.
产前影像学的进展改善了胎儿心血管系统的检查。胎儿超声心动图有助于先天性心脏病(CHD)的产前诊断,通过连续检查,可以评估胎儿心脏血流动力学,预测子宫内以及分娩时向产后循环过渡期间心血管解剖和功能异常的演变。这种方法能够在产前咨询时进行详细诊断,并有助于制定围产期管理计划,筛选出可能需要专门分娩计划、有产后血流动力学不稳定风险的胎儿。已证明,对严重新生儿CHD进行产前诊断和管理,对于改善患有这些疾病的新生儿的预后具有重要作用,能够在心脏介入或手术前及时稳定循环,从而降低围手术期发病和死亡风险。旨在对患有CHD的胎儿的严重程度和潜在产后损害进行风险分层的诊断方案已经制定出来,以识别那些可能在出生时或出生后几天内需要特殊干预的胎儿。此外,正在研究新的方法,以提高疾病严重程度预测的准确性。对产前诊断为CHD的新生儿进行围产期管理,需要产科、新生儿科和心脏病科密切合作。在本文中,将讨论患有CHD的胎儿的管理,总结用于对患有CHD的新生儿进行风险分层的子宫内和胎儿超声心动图检查结果,并回顾用于规划这些复杂新生儿的新生儿复苏和初始过渡护理的基本原则。