Leite Cavalcanti Alessandro, José de Macêdo Dário, Suely Barros Dantas Fernanda, Dos Santos Menezes Karla, Filipe Bezerra Silva Diego, Alves de Melo Junior William, Fabia Cabral Cavalcanti Alidianne
Programa de Pós-Graduação em Saúde Pública, Universidade Estadual da Paraíba, Avenida das Baraúnas, S/N-Campus Universitário, Bodocongó, Campina Grande 58109-753, Brazil.
Faculty of Medical Sciences, Campina Grande 58109-753, Brazil.
J Clin Med. 2018 Apr 24;7(5):90. doi: 10.3390/jcm7050090.
Low-level laser therapy has been widely used in treating many conditions, including oral mucositis. The purpose of this study was to evaluate the occurrence of oral mucositis in patients undergoing antineoplastic therapy submitted to preventive and therapeutic treatment with low-level laser therapy. This cross-sectional study was carried out with 51 children and adolescents of both sexes with malignant neoplasias who developed oral mucositis and underwent low-level laser therapy. Data were collected on sex, age, type and degree of neoplasia, region affected, and remission time. 64.7% of the patients were male and were between 3 and 6 years of age (39.2%). Acute lymphoid leukemia was the most frequent neoplasm (37.3%). Regarding the maximum oral mucositis, grade 2 (41.2%) was predominant, with jugal mucosa (29.9%) and tongue (17.7%) being the most affected regions. The majority of cases presented lesion remission time between 4 and 7 days (44.0%). Most patients were young, male, and diagnosed with acute lymphoid leukemia. Predominance of grade 2 oral mucositis was observed, with jugal mucosa and tongue being the most affected regions, with the majority of cases presenting lesion remission time between 4 and 7 days. Low-level laser therapy has been shown to be an essential therapy in the prevention and treatment of these lesions, since it is a non-invasive and low-cost method.
低强度激光疗法已被广泛应用于治疗多种病症，包括口腔黏膜炎。本研究的目的是评估接受抗肿瘤治疗的患者在接受低强度激光疗法预防性和治疗性治疗后口腔黏膜炎的发生情况。这项横断面研究对51名患有恶性肿瘤且发生口腔黏膜炎并接受低强度激光疗法的儿童和青少年进行，无论男女。收集了有关性别、年龄、肿瘤类型和程度、受影响区域以及缓解时间的数据。64.7%的患者为男性，年龄在3至6岁之间（39.2%）。急性淋巴细胞白血病是最常见的肿瘤（37.3%）。关于口腔黏膜炎的最大程度，2级（41.2%）最为常见，面颊黏膜（29.9%）和舌头（17.7%）是受影响最严重的区域。大多数病例的病变缓解时间在4至7天之间（44.0%）。大多数患者为年轻人、男性，被诊断为急性淋巴细胞白血病。观察到2级口腔黏膜炎最为常见，面颊黏膜和舌头是受影响最严重的区域，大多数病例的病变缓解时间在4至7天之间。低强度激光疗法已被证明是预防和治疗这些病变的重要疗法，因为它是一种非侵入性且低成本的方法。
