Bañuelos-Chávez Karla Vanesa, Cerrillos-Gutiérrez José Ignacio, Nario Juan Carlos, Abundis-Jiménez Juan, Preciado-Rojas Priscila, Campos-Mariz Alejandro, Cortés-Sanabria Laura, Cueto-Manzano Alfonso Martín, Rojas-Campos Enrique
Unidad de Investigación Médica en Enfermedades Renales, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México Correo electrónico:
Rev Med Inst Mex Seguro Soc. 2017;55(Suppl 2):S151-7.
Vascular calcification (VC), it is a clinical condition highly associated to Chronic Kidney Disease (CKD), CKD patients had as a primary death cause, the cardiovascular disease (CVD), among many non-traditional factors for CKD appears VC. The pathogenesis of VC it´s multifactorial and it´s in short terms a change of muscle vessels cells to a bone cell; this transformation it´s close related to Chronic Kidney Disease-Bone Metabolism Disorder (CKD-BMD), Vitamin D, phosphorus, calcium and parathyroid hormone are close related to VC. The diagnosis of VC can be done by different methods from Electron Beam Computed Tomography to plain X ray studies; there are many scores base on plain X ray studies that can predict mortality in patients with VC. In our setting there is scarce information regarding VC in dialysis patients, the available information show a higher frequency (~50%) and severe; predictors to the VC in our setting are: age, serum HDL and alkaline phosphatase. It is necessary in the primary care setting the evaluation of VC in order to prevent it appearing. There is not an effective treatment to VC so it´s necessary search for strategies to prevent it.
血管钙化（VC）是一种与慢性肾脏病（CKD）高度相关的临床病症，CKD患者的主要死因是心血管疾病（CVD），在CKD的诸多非传统因素中出现了VC。VC的发病机制是多因素的，短期内是肌肉血管细胞向骨细胞的转变；这种转变与慢性肾脏病 - 骨代谢紊乱（CKD - BMD）密切相关，维生素D、磷、钙和甲状旁腺激素与VC密切相关。VC的诊断可以通过从电子束计算机断层扫描到普通X线检查等不同方法进行；基于普通X线检查有许多评分可以预测VC患者的死亡率。在我们的研究环境中，关于透析患者VC的信息很少，现有信息显示其发生率较高（约50%）且病情严重；在我们的研究环境中，VC的预测因素有：年龄、血清高密度脂蛋白和碱性磷酸酶。在初级保健环境中，有必要对VC进行评估以预防其出现。目前尚无针对VC的有效治疗方法，因此有必要寻找预防策略。
