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[心肌肥大、动脉高血压与心源性猝死]

[Myocardial hypertrophy, arterial hypertension and sudden cardiac death].

作者信息

Vikhert A M, Zhdanov V S, Sokolova R I, Galakhov I E, Veselova S P

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1988;11(1):12-9.

PMID:2969734
Abstract

721 cases of sudden coronary death (SCD) of men aged 30-59 were studied. It was found out that SCD happened in majority of cases in subjects with increased weight of heart: 44.2% of patients had heart weight of 500 g or more. A special histomorphometric study of kidneys (345 cases of SCD) revealed arterial hypertension (AH) in 41.2% of cases, which far exceeded AH incidence in the population of men of equal age. Nevertheless, not in all cases of SCD was myocardial hypertrophy caused by AH. In patients with no AH myocardial hypertrophy was usually caused by postinfarction cardiosclerosis. In certain cases of SCD without cardiosclerosis accompanied by manifest myocardial hypertrophy there were signs of dilatative or hypertrophic cardiomyopathy. The obtained results suggest that AH and increased weight of heart should be considered factors predisposing to SCD.

摘要

对721例年龄在30至59岁之间的男性冠心病猝死(SCD)病例进行了研究。结果发现,大多数SCD病例发生在心脏重量增加的受试者中:44.2%的患者心脏重量达到或超过500克。对肾脏进行的一项特殊组织形态计量学研究(345例SCD病例)显示,41.2%的病例存在动脉高血压(AH),这远远超过了同年龄男性人群中AH的发病率。然而,并非所有SCD病例中的心肌肥厚都是由AH引起的。在没有AH的患者中,心肌肥厚通常是由心肌梗死后的心硬化引起的。在某些没有心硬化但伴有明显心肌肥厚的SCD病例中,有扩张型或肥厚型心肌病的迹象。所得结果表明,AH和心脏重量增加应被视为SCD的易感因素。

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