肝炎相关性再生障碍性贫血：3例与甲型肝炎病毒相关病例报告

Hepatitis-associated Aplastic Anemia: A Report of 3 Cases Associated With HAV.

作者信息

Alsakkal Mohammad, Al-Khateeb Mohammad, Alhalaby Mohammad, Khouri Lina

机构信息

Faculty of Medicine.

Department of Pediatrics, Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic.

出版信息

J Pediatr Hematol Oncol. 2019 Apr;41(3):e164-e166. doi: 10.1097/MPH.0000000000001199.

DOI:10.1097/MPH.0000000000001199

PMID:29697580

Abstract

Aplastic anemia is a rare complication of viral hepatitis. We present 3 cases of hepatitis-associated aplastic anemia after hepatitis A virus infection. One of our cases is the first reported case of hepatitis-associated aplastic anemia after fulminant hepatitis A infection. Patient characteristics were consistent with older reports with regard to age and sex. All 3 patients were male individuals under the age of 20. In addition, all 3 patients had A+ blood group. Outcomes in our series were poor because of the unavailability of antithymocyte globulin and bone marrow transplantation.

摘要

再生障碍性贫血是病毒性肝炎的一种罕见并发症。我们报告了3例甲型肝炎病毒感染后发生的肝炎相关性再生障碍性贫血病例。其中1例是暴发性甲型肝炎感染后发生的肝炎相关性再生障碍性贫血的首例报告病例。患者的特征在年龄和性别方面与既往报告一致。所有3例患者均为20岁以下男性。此外，所有3例患者血型均为A+。由于无法获得抗胸腺细胞球蛋白和进行骨髓移植，我们这组病例的预后较差。