Progress Educational Trust, 140 Grays Inn Road, London, UK.
Br Med Bull. 2018 Jun 1;126(1):5-12. doi: 10.1093/bmb/ldy015.
Human genome editing is an area of growing prominence, with many potential therapeutic applications.
A project by two UK charities, whose participants included fertility sector patients and practitioners and also people affected by genetic disease and rare disease. Scientific research into, and wider discussion of, genomics and genome editing.
There is a need for improved public and professional understanding of genome editing.
The way genome editing is discussed is often inconsistent and confusing. Simply defining and explaining the term 'genome' can present challenges.
There are approaches that lend themselves to achieving greater clarity and coherence in discussion of genome editing.
People's understanding should ideally be able to withstand and evolve alongside current developments in genome editing, rather than being tied firmly to specific aspects of genome editing (which may in future be supplanted).
人类基因组编辑是一个日益受到关注的领域,具有许多潜在的治疗应用。
两个英国慈善机构的项目,其参与者包括生育领域的患者和从业者,以及受遗传疾病和罕见病影响的人。对基因组学和基因组编辑的科学研究和更广泛的讨论。
需要提高公众和专业人士对基因组编辑的理解。
基因组编辑的讨论方式往往不一致且令人困惑。简单地定义和解释“基因组”一词就可能带来挑战。
有一些方法可以在讨论基因组编辑时实现更大的清晰度和一致性。
人们的理解应该能够理想地承受并随着基因组编辑的当前发展而发展,而不是与基因组编辑的特定方面紧密联系(这些方面在未来可能会被取代)。