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[透析患者中的甲状腺疾病]

[Thyroid disorders among dialysis patients].

作者信息

Chávez-Valencia Venice, Roa-Córdova Martha Alicia, Mejía-Rodríguez Oliva, Viveros-Sandoval Martha Eva, Orizaga-de la Cruz Citlalli, Aguilar-Bixano Omar, Rodríguez-Oseguera Héctor Gerardo, Álvarez-Aguilar Cleto

机构信息

Hospital General Regional No. 1, Instituto Mexicano del Seguro Social, Morelia, Michoacán de Ocampo, México Correo electrónico:

出版信息

Rev Med Inst Mex Seguro Soc. 2017;55(Suppl 2):S188-94.

Abstract

The thyroid gland and the kidney are closely related. Thyroid hormones (TH) contribute to the homeostasis of the human being through complex interactions of fluids and electrolytes, protein synthesis, etc. The effects on the kidney of TH may be pre renal or direct actions. Decreasing glomerular filtration (GF) this balance especially in advanced stages of chronic kidney disease (CKD) is altered. CKD is linked to alterations in TH levels and/or metabolism, resulting in a high prevalence of subclinical hypothyroidism and low free triiodothyronine (FT3) syndrome. These alterations are linked in micro inflammation, endothelial damage, cardiac abnormalities, and high mortality. In this study, we describe the most common thyroid abnormalities reported in CKD with dialytic stage approach.

摘要

甲状腺与肾脏密切相关。甲状腺激素(TH)通过体液和电解质的复杂相互作用、蛋白质合成等,对人体的内环境稳定发挥作用。TH对肾脏的影响可能是肾前性的或直接作用。肾小球滤过(GF)的降低尤其在慢性肾脏病(CKD)晚期会改变这种平衡。CKD与TH水平和/或代谢的改变有关,导致亚临床甲状腺功能减退和低游离三碘甲状腺原氨酸(FT3)综合征的高患病率。这些改变与微炎症、内皮损伤、心脏异常和高死亡率有关。在本研究中,我们采用透析分期方法描述了CKD中报告的最常见的甲状腺异常情况。

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