Levrini Luca, Salone Giuseppa Sara, Ramirez-Yanez German O
J Clin Pediatr Dent. 2018;42(3):236-239. doi: 10.17796/1053-4628-42.3.13. Epub 2018 Apr 26.
The purpose of this study was to determine the efficacy of the Myobrace/MyOSA myofunctional appliance for the treatment of mild to moderate Obstructive Sleep Apnea (OSA) in children, by means of the Apnea/Hypopnea Index (AHI).
Nine children with a diagnosis of mild to moderate OSA were included in the study. The subjects wore the Myobrace/MyOSA myofunctional appliance for a period of 90 days. The initial AHI, determined by means of a sleep test, was used as baseline (To), and a second AHI, computed at the end of the experimental period, was used as final data (T). The differences between the AHIs at To and T were calculated (diff AHI) and used for statistical purposes. The level of Oxygen Saturation (SaO) was also recorded before and after treatment, and their differences calculated as diff SaO. Statistical analysis was performed with a paired-t- test and statistical significance was established at 95 per cent level of confidence.
A statistical significant reduction in the AHI of the studied subjects was computed at the end of the experimental period (p = 0.0425). Although there was an improvement in the SaO, it did not reach a statistically significant difference.
The present results suggest that the Myobrace/MyOSA myofunctional appliance can be an alternative to treat mild to moderate OSA in children. However further studies are necessary to determine the stability of the results after treatment.
本研究旨在通过呼吸暂停低通气指数（AHI）来确定肌功能矫治器Myobrace/MyOSA治疗儿童轻至中度阻塞性睡眠呼吸暂停（OSA）的疗效。
9名诊断为轻至中度OSA的儿童纳入本研究。受试者佩戴Myobrace/MyOSA肌功能矫治器90天。通过睡眠测试确定的初始AHI用作基线（T0），在实验期结束时计算的第二个AHI用作最终数据（T）。计算T0和T时AHI的差异（差值AHI）并用于统计分析。治疗前后还记录了血氧饱和度（SaO）水平，并计算其差异作为差值SaO。采用配对t检验进行统计分析，在95%置信水平确定统计学意义。
在实验期结束时，计算出研究对象的AHI有统计学意义的降低（p = 0.0425）。虽然SaO有所改善，但未达到统计学显著差异。
目前的结果表明，Myobrace/MyOSA肌功能矫治器可以作为治疗儿童轻至中度OSA的一种替代方法。然而，需要进一步研究以确定治疗后结果的稳定性。
