Naik Milind N, Pujari Aditi, Ali Mohammad Javed, Kaliki Swathi, Dave Tarjani Vivek
Department of Ophthalmic Plastic Surgery, LV Prasad Eye Institute, Hyderabad, India.
Department of Ophthalmic Plastic Surgery, LV Prasad Eye Institute, Hyderabad, India.
J AAPOS. 2018 Jun;22(3):179-182.e1. doi: 10.1016/j.jaapos.2017.12.018. Epub 2018 Apr 24.
To report a single-center experience with nonsurgical correction of epiblepharon using hyaluronic acid gel.
The medical records of consecutive patients with symptomatic epiblepharon treated over a 3-year period with hyaluronic acid gel injection were reviewed retrospectively. Hyaluronic acid gel was injected transcutaneously into the suborbicularis plane to obliterate the abnormal skin fold or evert the eyelid margin. Successful treatment was defined as eversion of the eyelid margin as assessed by lash-cornea touch.
Ten eyelids of 8 patients (7 girls [88%]) underwent transcutaneous hyaluronic acid gel injection for correction of epiblepharon. Average age at presentation was 16.5 months (range, 1-72 months). Two patients had bilateral involvement. Of 10 eyelids, 8 had a distinct skin fold with a "valley" above it. Nine of 10 eyelids had lash-cornea touch in the primary gaze; 1 in downgaze. All 10 eyes had punctate corneal epitheliopathy on fluorescein staining. An average of 0.19 ml (range, 0.1-0.3 ml) of hyaluronic acid gel was injected per eyelid. After injection, 9 of 10 eyelids showed no lash-cornea touch in downgaze, and all 10 eyelids showed resolution of symptoms and epitheliopathy. Patients remained symptom-free for an average final follow-up of 19.1 months (range, 5-42 months). No procedure-related complications were noted.
In our small case series, transcutaneous hyaluronic acid gel injection into the lower eyelid effectively corrected symptomatic epiblepharon; the effect was long lasting.
报告使用透明质酸凝胶非手术矫正睑缘赘皮的单中心经验。
回顾性分析连续3年接受透明质酸凝胶注射治疗的有症状睑缘赘皮患者的病历。经皮将透明质酸凝胶注射到眼轮匝肌下平面，以消除异常皮肤褶皱或翻转眼睑边缘。成功治疗定义为通过睫毛-角膜接触评估眼睑边缘翻转。
8例患者（7名女孩[88%]）的10只眼睑接受了经皮透明质酸凝胶注射以矫正睑缘赘皮。就诊时的平均年龄为16.5个月（范围1 - 72个月）。2例患者为双侧受累。10只眼睑中，8只具有明显的皮肤褶皱且上方有“沟”。10只眼睑中有9只在第一眼位时存在睫毛-角膜接触；1只在向下注视时存在。所有10只眼在荧光素染色时均有角膜上皮点状病变。每只眼睑平均注射0.19毫升（范围0.1 - 0.3毫升）透明质酸凝胶。注射后，10只眼睑中有9只在向下注视时无睫毛-角膜接触，且所有10只眼睑的症状和上皮病变均得到缓解。患者在最后一次随访时平均19.1个月（范围5 - 42个月）无症状。未观察到与手术相关的并发症。
在我们的小病例系列中，经皮向下眼睑注射透明质酸凝胶可有效矫正有症状的睑缘赘皮；效果持久。
