Rao Raksha, Honavar Santosh G, Mulay Kaustubh, Reddy Vijay Anand P
Ocular Oncology Service, Hyderabad, Telangana, India.
Ocular Oncology Service, Hyderabad, Telangana, India.
J AAPOS. 2018 Jun;22(3):235-237.e2. doi: 10.1016/j.jaapos.2017.11.013. Epub 2018 Apr 24.
Diffuse anterior retinoblastoma is an infrequent presentation in which the tumor is confined to the anterior segment, and there is no retinal mass. An 18-month-old Asian Indian boy presented with white spots in the left eye. There were extensive anterior segment seeds without a retinal tumor. Fine-needle aspiration biopsy confirmed the diagnosis of retinoblastoma, and the patient received intravenous chemotherapy with a combination of vincristine-carboplatin-etoposide, periocular topotecan, and intravitreal topotecan to achieve complete tumor regression.
弥漫性前部视网膜母细胞瘤是一种罕见的表现形式，肿瘤局限于眼前段，且无视网膜肿块。一名18个月大的亚洲印度男孩左眼出现白色斑点。存在广泛的眼前段播散灶，但无视网膜肿瘤。细针穿刺活检确诊为视网膜母细胞瘤，该患者接受了长春新碱-卡铂-依托泊苷联合静脉化疗、眼周拓扑替康和玻璃体内拓扑替康治疗，以实现肿瘤完全消退。
