Shimizu Yasushi, Fukuda Jun, Kumasawa Yukiyo, Tanaka Toshinobu
Division of Obstetrics and Gynecology, Department of Reproductive and Development Medicine, Akita University School of Medicine, Akita, Japan.
Reprod Med Biol. 2004 May 20;3(2):95-98. doi: 10.1111/j.1447-0578.2004.00057.x. eCollection 2004 Jun.
Three women with adenomyosis conceived by fertilization-embryo transfer (IVF-ET), but miscarried in the second trimester. The uterus in each case was inflamed post-partum and one patient underwent total abdominal hysterectomy as treatment for the severe inflammation. Although the mechanism of the miscarriages is unclear, these cases strongly suggest that it is related to the inflammation of the myometrium associated with adenomyosis, and that such pregnancies have a high risk of not continuing to term. Preventing inflammation could result in a live birth. (Reprod Med Biol 2004; 3: 95-98).
三名患有子宫腺肌病的女性通过体外受精-胚胎移植(IVF-ET)受孕,但在孕中期流产。每例患者产后子宫均发生炎症,其中一名患者接受了全腹子宫切除术以治疗严重炎症。尽管流产机制尚不清楚,但这些病例强烈提示,流产与子宫腺肌病相关的子宫肌层炎症有关,且此类妊娠足月分娩的风险很高。预防炎症可能会实现活产。(《生殖医学与生物学》2004年;3:95-98)