Kagabu Satosi, Umezu Motoaki
Faculty of Agriculture, Yamaguchi University, Yamaguchi-shi and.
Faculty of Agriculture, Utsunomiya University, Utsunomiya-shi, Japan.
Reprod Med Biol. 2005 May 3;4(2):149-152. doi: 10.1111/j.1447-0578.2005.00095.x. eCollection 2005 Jun.
To investigate the effect of the number of pups being nursed on the survival of mouse ovarian tissue transplanted into the post-partum rat uterus. Mouse ovarian tissue was transplanted into the uterine horn of post-partum rats. The number of pups nursed by each recipient rat was adjusted in a manner predetermined. Examinations were undertaken at 1-11 weeks after transplantation. Ovarian tissue containing healthy follicles was considered to have taken successfully. In rats with 12 pups, ovarian tissue remained viable at 11 weeks post-transplantation. No viable ovarian tissue remained when there were one or two pups. Viability improved as the number of pups increased. When mouse ovarian tissue is transplanted into post-partum lactating rats, viability improves as the number of pups increases. We concluded that these findings may be explained in terms of progesterone levels in the recipient rats. (Reprod Med Biol 2005; : 149-152).
为研究哺育幼崽数量对移植到产后大鼠子宫内的小鼠卵巢组织存活的影响。将小鼠卵巢组织移植到产后大鼠的子宫角。以预先确定的方式调整每只受体大鼠哺育的幼崽数量。在移植后1至11周进行检查。含有健康卵泡的卵巢组织被认为移植成功。在哺育12只幼崽的大鼠中，卵巢组织在移植后11周仍保持存活。当只有1只或2只幼崽时，没有存活的卵巢组织残留。随着幼崽数量的增加，存活率提高。当小鼠卵巢组织移植到产后哺乳期大鼠体内时，随着幼崽数量的增加，存活率提高。我们得出结论，这些发现可能可以用受体大鼠体内的孕酮水平来解释。（《生殖医学与生物学》2005年；：149 - 152）
