Nagao Koichi, Kobayashi Hideyuki, Nakajima Koichi, Takanami Masaharu, Miura Kazukiyo, Ishii Nobuhisa
Department of Urology, Toho University School of Medicine, Tokyo, Japan.
Reprod Med Biol. 2008 Aug 3;7(3):105-114. doi: 10.1111/j.1447-0578.2008.00206.x. eCollection 2008 Sep.
The aim of the present study was to investigate the assessment of currently prescribed drugs and approaches to overall erectile dysfunction (ED) therapy. A large-scale questionnaire survey was conducted in patients with ED who had taken an ED drug in the past 2 months. Of the 308 patients surveyed, 23% became aware of having ED more than 3 years ago. In the early stages, the patients frequently experienced 'anxiety and a sense of loss' and 'irritation and powerlessness'. The ED drugs taken were sildenafil and vardenafil in 65 and 31% of the patients, respectively. Although their efficacy was generally high, approximately 80% of the patients (younger patients in particular) experienced some problems with these medications. As negative assessments, the difficulty in finding a good time to take the drug and the strange sensation of the drug forcing the patient to have an erection were pointed out. Use of an ED drug such as tadalafil, which produces long-lasting effects and allows more spontaneity in sexual activity, will improve ED symptoms in a favorable manner, and will not only improve the self-image of the ED patients, leading to activation and fulfillment of their lives as a whole, but will also enhance the satisfaction and security of their partners. (Reprod Med Biol 2008; : 105-114).
本研究的目的是调查当前处方药的评估情况以及勃起功能障碍(ED)整体治疗方法。对过去2个月内服用过ED药物的ED患者进行了大规模问卷调查。在接受调查的308名患者中,23%的患者在3年多以前就意识到自己患有ED。在疾病早期,患者经常经历“焦虑和失落感”以及“烦躁和无助感”。服用ED药物的患者中,分别有65%和31%服用了西地那非和伐地那非。尽管它们的疗效总体较高,但约80%的患者(尤其是年轻患者)在使用这些药物时出现了一些问题。作为负面评价,指出了难以找到合适的服药时间以及药物迫使患者勃起的奇怪感觉。使用他达拉非等具有长效作用且能使性活动更具自发性的ED药物,将以良好的方式改善ED症状,不仅会改善ED患者的自我形象,促使他们全面活跃起来并充实生活,还会提高其伴侣的满意度和安全感。(《生殖医学与生物学》2008年;:105 - 114)