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复发性多软骨炎伴脑膜脑炎患者的细胞增多症:病例报告

Pleocytosis in a patient with relapsing polychondritis accompanied by meningoencephalitis: a case report.

作者信息

Cao Jie, Zhang Min

机构信息

Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, 430030, China.

出版信息

BMC Neurol. 2018 Apr 25;18(1):53. doi: 10.1186/s12883-018-1059-7.

DOI:10.1186/s12883-018-1059-7
PMID:29699514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5921442/
Abstract

BACKGROUND

Relapsing polychondritis (RP) is an uncommon immune-related disease with unknown causes. It is characterized by inflammation of cartilaginous or non-cartilaginous structures, such as the ears, nose, respiratory tract, eyes, and joints. Neurological involvement is rare in RP.

CASE PRESENTATION

We report a case of pleocytosis in a 64-year-old man diagnosed as having RP with meningoencephalitis. The patient's condition markedly improved following methylprednisolone treatment.

CONCLUSIONS

To our knowledge, this is the first report of recurrent pleocytosis in a patient with RP accompanied by meningoencephalitis. Steroid pulse therapy is effective in most cases, and early diagnosis is of importance.

摘要

背景

复发性多软骨炎(RP)是一种病因不明的罕见免疫相关疾病。其特征是软骨或非软骨结构发炎,如耳朵、鼻子、呼吸道、眼睛和关节。RP患者神经系统受累罕见。

病例报告

我们报告一例64岁男性被诊断为患有RP合并脑膜脑炎,脑脊液细胞增多。患者经甲泼尼龙治疗后病情明显改善。

结论

据我们所知,这是首例RP合并脑膜脑炎患者反复出现脑脊液细胞增多的报告。大多数情况下,类固醇冲击疗法有效,早期诊断很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b95f/5921442/1ed9c296c8c3/12883_2018_1059_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b95f/5921442/06a06401468c/12883_2018_1059_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b95f/5921442/1ed9c296c8c3/12883_2018_1059_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b95f/5921442/06a06401468c/12883_2018_1059_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b95f/5921442/1ed9c296c8c3/12883_2018_1059_Fig2_HTML.jpg

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