Cao Jie, Zhang Min
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan, 430030, China.
BMC Neurol. 2018 Apr 25;18(1):53. doi: 10.1186/s12883-018-1059-7.
Relapsing polychondritis (RP) is an uncommon immune-related disease with unknown causes. It is characterized by inflammation of cartilaginous or non-cartilaginous structures, such as the ears, nose, respiratory tract, eyes, and joints. Neurological involvement is rare in RP.
We report a case of pleocytosis in a 64-year-old man diagnosed as having RP with meningoencephalitis. The patient's condition markedly improved following methylprednisolone treatment.
To our knowledge, this is the first report of recurrent pleocytosis in a patient with RP accompanied by meningoencephalitis. Steroid pulse therapy is effective in most cases, and early diagnosis is of importance.
复发性多软骨炎(RP)是一种病因不明的罕见免疫相关疾病。其特征是软骨或非软骨结构发炎,如耳朵、鼻子、呼吸道、眼睛和关节。RP患者神经系统受累罕见。
我们报告一例64岁男性被诊断为患有RP合并脑膜脑炎,脑脊液细胞增多。患者经甲泼尼龙治疗后病情明显改善。
据我们所知,这是首例RP合并脑膜脑炎患者反复出现脑脊液细胞增多的报告。大多数情况下,类固醇冲击疗法有效,早期诊断很重要。