用于帕金森病的利苏瑞德输液泵。两例报告。

Lisuride infusion pump in Parkinson's disease. A report of two cases.

作者信息

Gershanik O S, Scipioni O, García S

机构信息

Department of Neurology, Hospital Francés, Buenos Aires, Argentina.

出版信息

J Neural Transm Suppl. 1988;27:85-90. doi: 10.1007/978-3-7091-8954-2_10.

DOI:10.1007/978-3-7091-8954-2_10

PMID:2969955

Abstract

Two patients, ages 66 and 72, with complications of chronic levodopa therapy (random fluctuations, end of dose deterioration and dyskinesias) who were treated with Lisuride by means of a portable subcutaneous infusion pump are reported. Results obtained show significant improvement in disability through a net increase in the number of hours spent "on". Dyskinesias remained unmodified. Limiting psychiatric side effects were observed in one of the patients. Practical and technical aspects of the management of this therapeutic method are discussed.

摘要

报告了两名分别为66岁和72岁的患者，他们患有慢性左旋多巴治疗的并发症（随机波动、剂末恶化和异动症），通过便携式皮下输注泵接受了利苏瑞ide治疗。所获得的结果显示，通过“开启”时间净增加，残疾状况有显著改善。异动症未发生变化。在其中一名患者中观察到了有限的精神方面副作用。讨论了这种治疗方法管理中的实际和技术方面。