Fenichel P, Zartarian M, Grimaud D, Brucker F, Morand P, Harter M, Fredenrich A
Service d'Endocrinologie-Nutrition-Diabétologie et Médecine interne, Hôpital de l'Archet, Nice.
Presse Med. 1988 Jul 2;17(26):1345-8.
The prognostic factors and therapeutic approaches in myxoedema coma--a rare but serious medical emergency--were re-evaluated from a retrospective study of 10 cases. The immediate respiratory risk can be prevented by referring these patients immediately to an intensive care unit. The patient's cardiovascular status before and after coma determines the prognosis for life and serves as guideline to treatment. Hormone replacement therapy with initial injection of a loading dose of thyroxine seems to improve the prognosis by ensuring rapid recovery of the principal vital functions.
