黏液性水肿昏迷

[Myxedema coma].

作者信息

Fonseca F, Cortez L, Guerra L, Afonso A, Agapito A, Malheiro F, da Costa C

机构信息

Unidade de Endocrinologia, H. Curry Cabral, Lisboa.

出版信息

Acta Med Port. 1992 Dec;5(11):613-5.

PMID:1293958

Abstract

Five patients, 4 female and 1 male, aged 45 to 73, were observed in myxedema coma between 1984 and 1992. In three patients hypothyroidism was not known. Depressed consciousness, hypothermia, bradycardia and no goiter were common to all and a precipitating factor could be identified in 3 of them. Therapy included L-thyroxine and/or triiodothyronine by nasogastric tube, hydrocortisone and supportive measures. Outcome was good in the 2 patients with known precipitating event, less impaired consciousness and normalization of body temperature by the third day of treatment.

摘要

1984年至1992年间，我观察了5例黏液水肿性昏迷患者，其中4例女性，1例男性，年龄在45岁至73岁之间。3例患者此前未知患有甲状腺功能减退症。所有患者均有意识障碍、体温过低、心动过缓且无甲状腺肿大，其中3例可明确诱因。治疗措施包括经鼻胃管给予左旋甲状腺素和/或三碘甲状腺原氨酸、氢化可的松及支持治疗。2例已知有诱发事件的患者治疗效果良好，意识障碍较轻，治疗第三天体温恢复正常。