Lammer J, Karnel F
Department of Radiology, Hospital of the University of Graz, Austria.
Radiology. 1988 Sep;168(3):733-7. doi: 10.1148/radiology.168.3.2970099.
Percutaneous transluminal laser angioplasty (PTLA) with a metal contact probe and a sapphire contact probe was performed under experimental conditions and in 88 patients with femoropopliteal artery occlusions. The experiment revealed that more ablation was caused by the sapphire probe than by the metal probe. Because of heat accumulation in subsurface tissue layers the metal probe caused a three to four times larger zone of thermal necrosis surrounding the tissue defect. Clinically both contact probes revealed similar results. The initial rate of recanalization of femoropopliteal artery occlusions with a mean length of 8 cm was 78% (metal probe) to 82% (sapphire probe), and the perforation rate was 14% (metal probe) to 8% (sapphire probe). Doppler ultrasound examinations after 6 months revealed a patency rate of 84%. PTLA has proved to be a successful and safe procedure for recanalization of arterial obstructions that are not appropriate for fibrinolysis.
在实验条件下以及对88例股腘动脉闭塞患者进行了使用金属接触探头和蓝宝石接触探头的经皮腔内激光血管成形术(PTLA)。实验表明,蓝宝石探头造成的消融比金属探头更多。由于表层下组织层的热量积聚,金属探头在组织缺损周围造成的热坏死区域大三到四倍。临床上,两种接触探头显示出相似的结果。平均长度为8厘米的股腘动脉闭塞的初始再通率为78%(金属探头)至82%(蓝宝石探头),穿孔率为14%(金属探头)至8%(蓝宝石探头)。6个月后的多普勒超声检查显示通畅率为84%。PTLA已被证明是一种成功且安全的用于对不适合纤溶治疗的动脉阻塞进行再通的手术。